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Fibroblast subtypes define a metastatic matrisome in breast cancer.
Brechbuhl HM, Barrett AS, Kopin E, Hagen JC, Han AL, Gillen AE, Finlay-Schultz J, Cittelly DM, Owens P, Horwitz KB, Sartorius CA, Hansen K, Kabos P. Brechbuhl HM, et al. Among authors: owens p. JCI Insight. 2020 Feb 27;5(4):e130751. doi: 10.1172/jci.insight.130751. JCI Insight. 2020. PMID: 32045383 Free PMC article.
Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.
Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD. Lennon S, et al. Among authors: owens p. Clin Cancer Res. 2019 Jun 1;25(11):3352-3365. doi: 10.1158/1078-0432.CCR-18-2811. Epub 2019 Apr 3. Clin Cancer Res. 2019. PMID: 30944125 Free PMC article.
Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer.
Shee K, Jiang A, Varn FS, Liu S, Traphagen NA, Owens P, Ma CX, Hoog J, Cheng C, Golub TR, Straussman R, Miller TW. Shee K, et al. Among authors: owens p. FASEB J. 2019 Feb;33(2):1644-1657. doi: 10.1096/fj.201801241R. Epub 2018 Aug 30. FASEB J. 2019. PMID: 30161001 Free PMC article.
BMP4-mediated growth inhibition was dependent on type I receptor activin receptor-like kinase (ALK)3-dependent phosphorylation (P) of mothers against decapentaplegic homolog (SMAD/P-SMAD)1 and 5, which could be reversed by BMP receptor inhibitors and ALK3 knockdown. …
BMP4-mediated growth inhibition was dependent on type I receptor activin receptor-like kinase (ALK)3-dependent phosphorylation (P) of …
Mechanobiology of Bone Metastatic Cancer.
Sarazin BA, Ihle CL, Owens P, Lynch ME. Sarazin BA, et al. Among authors: owens p. Curr Osteoporos Rep. 2021 Dec;19(6):580-591. doi: 10.1007/s11914-021-00704-9. Epub 2021 Nov 3. Curr Osteoporos Rep. 2021. PMID: 34729693 Review.
miR-31 Displays Subtype Specificity in Lung Cancer.
Davenport ML, Echols JB, Silva AD, Anderson JC, Owens P, Yates C, Wei Q, Harada S, Hurst DR, Edmonds MD. Davenport ML, et al. Among authors: owens p. Cancer Res. 2021 Apr 15;81(8):1942-1953. doi: 10.1158/0008-5472.CAN-20-2769. Epub 2021 Feb 8. Cancer Res. 2021. PMID: 33558335 Free PMC article.
578 results