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Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo.
Wymann S, Mischnik M, Leong D, Ghosh S, Tan X, Cao H, Kuehnemuth B, Powers GA, Halder P, de Souza MJ, James HS, Tomasetig V, Lind H, Rossato P, Owczarek CM, Ow SY, Dower SK, Baz Morelli A, Rowe T, Hardy MP. Wymann S, et al. Among authors: owczarek cm. Biochem J. 2022 May 13;479(9):1007-1030. doi: 10.1042/BCJ20220054. Biochem J. 2022. PMID: 35470373
Targeting the Human βc Receptor Inhibits Contact Dermatitis in a Transgenic Mouse Model.
Yip KH, McKenzie D, Ramshaw HS, Chao J, McClure BJ, Raquet E, Kraushaar T, Röder J, Maxwell M, Alhamdoosh M, Hammet A, Fong JH, Zeglinski K, Monaghan K, Pant H, Grimbaldeston MA, Vairo G, Wilson NJ, Owczarek CM, Hercus TR, Lopez AF, Tumes DJ. Yip KH, et al. Among authors: owczarek cm. J Invest Dermatol. 2022 Apr;142(4):1103-1113.e11. doi: 10.1016/j.jid.2021.07.183. Epub 2021 Sep 17. J Invest Dermatol. 2022. PMID: 34537191 Free article.
Modular Platform for the Development of Recombinant Hemoglobin Scavenger Biotherapeutics.
Buzzi RM, Owczarek CM, Akeret K, Tester A, Pereira N, Butcher R, Brügger-Verdon V, Hardy MP, Illi M, Wassmer A, Vallelian F, Humar R, Hugelshofer M, Buehler PW, Gentinetta T, Schaer DJ. Buzzi RM, et al. Among authors: owczarek cm. Mol Pharm. 2021 Aug 2;18(8):3158-3170. doi: 10.1021/acs.molpharmaceut.1c00433. Epub 2021 Jul 22. Mol Pharm. 2021. PMID: 34292741 Free article.
Glycoproteomic measurement of site-specific polysialylation.
Pelingon R, Pegg CL, Zacchi LF, Phung TK, Howard CB, Xu P, Hardy MP, Owczarek CM, Schulz BL. Pelingon R, et al. Among authors: owczarek cm. Anal Biochem. 2020 May 1;596:113625. doi: 10.1016/j.ab.2020.113625. Epub 2020 Feb 20. Anal Biochem. 2020. PMID: 32088200
46 results