Overstreet MG - Search Results

1

Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1⁺ Activated T Cells.

Dovedi SJ, Elder MJ, Yang C, Sitnikova SI, Irving L, Hansen A, Hair J, Jones DC, Hasani S, Wang B, Im SA, Tran B, Subramaniam DS, Gainer SD, Vashisht K, Lewis A, Jin X, Kentner S, Mulgrew K, Wang Y, Overstreet MG, Dodgson J, Wu Y, Palazon A, Morrow M, Rainey GJ, Browne GJ, Neal F, Murray TV, Toloczko AD, Dall'Acqua W, Achour I, Freeman DJ, Wilkinson RW, Mazor Y. Dovedi SJ, et al. Among authors: overstreet mg. Cancer Discov. 2021 May;11(5):1100-1117. doi: 10.1158/2159-8290.CD-20-1445. Epub 2021 Jan 8. Cancer Discov. 2021. PMID: 33419761

2

Preclinical Characterization of an Antibody-Drug Conjugate Targeting CS-1 and the Identification of Uncharacterized Populations of CS-1-Positive Cells.

Chen R, Rajan S, Overstreet MG, Hurt EM, Thomas SB, Muniz-Medina V, Ward C, Sadowska A, Fleming R, Karanth S, Breen S, Zheng B, Wu Y, Iverson WO, Novick S, O'Day T, Shah DP, Dimasi N, Tiberghien AC, Osbourn J, Walker J. Chen R, et al. Among authors: overstreet mg. Mol Cancer Ther. 2020 Aug;19(8):1649-1659. doi: 10.1158/1535-7163.MCT-19-0482. Epub 2020 May 13. Mol Cancer Ther. 2020. PMID: 32404408

3

HER2 antibody-drug conjugate controls growth of breast cancer brain metastases in hematogenous xenograft models, with heterogeneous blood-tumor barrier penetration unlinked to a passive marker.

Gril B, Wei D, Zimmer AS, Robinson C, Khan I, Difilippantonio S, Overstreet MG, Steeg PS. Gril B, et al. Among authors: overstreet mg. Neuro Oncol. 2020 Nov 26;22(11):1625-1636. doi: 10.1093/neuonc/noaa118. Neuro Oncol. 2020. PMID: 32386414 Free PMC article.

4

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis.

Gaylo A, Overstreet MG, Fowell DJ. Gaylo A, et al. Among authors: overstreet mg. J Vis Exp. 2016 Mar 25;(109):e53585. doi: 10.3791/53585. J Vis Exp. 2016. PMID: 27078264 Free PMC article.

5

Inflammation-induced interstitial migration of effector CD4⁺ T cells is dependent on integrin αV.

Overstreet MG, Gaylo A, Angermann BR, Hughson A, Hyun YM, Lambert K, Acharya M, Billroth-Maclurg AC, Rosenberg AF, Topham DJ, Yagita H, Kim M, Lacy-Hulbert A, Meier-Schellersheim M, Fowell DJ. Overstreet MG, et al. Nat Immunol. 2013 Sep;14(9):949-58. doi: 10.1038/ni.2682. Epub 2013 Aug 11. Nat Immunol. 2013. PMID: 23933892 Free PMC article.

6

Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels.

Hyun YM, Sumagin R, Sarangi PP, Lomakina E, Overstreet MG, Baker CM, Fowell DJ, Waugh RE, Sarelius IH, Kim M. Hyun YM, et al. Among authors: overstreet mg. J Exp Med. 2012 Jul 2;209(7):1349-62. doi: 10.1084/jem.20111426. Epub 2012 Jun 18. J Exp Med. 2012. PMID: 22711877 Free PMC article.

7

Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection.

Mock DJ, Hollenbaugh JA, Daddacha W, Overstreet MG, Lazarski CA, Fowell DJ, Kim B. Mock DJ, et al. Among authors: overstreet mg. PLoS Pathog. 2012;8(4):e1002635. doi: 10.1371/journal.ppat.1002635. Epub 2012 Apr 5. PLoS Pathog. 2012. PMID: 22496656 Free PMC article.

8

CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites.

Overstreet MG, Chen YC, Cockburn IA, Tse SW, Zavala F. Overstreet MG, et al. PLoS One. 2011 Jan 4;6(1):e15948. doi: 10.1371/journal.pone.0015948. PLoS One. 2011. PMID: 21245909 Free PMC article.

9

Adenovirus particles that display the Plasmodium falciparum circumsporozoite protein NANP repeat induce sporozoite-neutralizing antibodies in mice.

Palma C, Overstreet MG, Guedon JM, Hoiczyk E, Ward C, Karen KA, Zavala F, Ketner G. Palma C, et al. Among authors: overstreet mg. Vaccine. 2011 Feb 11;29(8):1683-9. doi: 10.1016/j.vaccine.2010.12.040. Epub 2011 Jan 1. Vaccine. 2011. PMID: 21199707 Free PMC article.

10

Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites.

Cockburn IA, Chen YC, Overstreet MG, Lees JR, van Rooijen N, Farber DL, Zavala F. Cockburn IA, et al. Among authors: overstreet mg. PLoS Pathog. 2010 May 6;6(5):e1000877. doi: 10.1371/journal.ppat.1000877. PLoS Pathog. 2010. PMID: 20463809 Free PMC article.

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