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IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation.
J Exp Med. 2023 Jun 5;220(6):e20212523. doi: 10.1084/jem.20212523. Epub 2023 Mar 28.
J Exp Med. 2023.
PMID: 36976181
Free PMC article.
TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation.
Irizarry-Caro RA, McDaniel MM, Overcast GR, Jain VG, Troutman TD, Pasare C.
Irizarry-Caro RA, et al. Among authors: overcast gr.
Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30628-30638. doi: 10.1073/pnas.2009778117. Epub 2020 Nov 16.
Proc Natl Acad Sci U S A. 2020.
PMID: 33199625
Free PMC article.
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T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity.
Jain A, Irizarry-Caro RA, McDaniel MM, Chawla AS, Carroll KR, Overcast GR, Philip NH, Oberst A, Chervonsky AV, Katz JD, Pasare C.
Jain A, et al. Among authors: overcast gr.
Nat Immunol. 2020 Jan;21(1):65-74. doi: 10.1038/s41590-019-0559-y. Epub 2019 Dec 17.
Nat Immunol. 2020.
PMID: 31848486
Free PMC article.
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