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Exploring microbial functional biodiversity at the protein family level-From metagenomic sequence reads to annotated protein clusters.
Baltoumas FA, Karatzas E, Paez-Espino D, Venetsianou NK, Aplakidou E, Oulas A, Finn RD, Ovchinnikov S, Pafilis E, Kyrpides NC, Pavlopoulos GA. Baltoumas FA, et al. Among authors: ovchinnikov s. Front Bioinform. 2023 Mar 3;3:1157956. doi: 10.3389/fbinf.2023.1157956. eCollection 2023. Front Bioinform. 2023. PMID: 36959975 Free PMC article. Review.
An atlas of protein homo-oligomerization across domains of life.
Schweke H, Pacesa M, Levin T, Goverde CA, Kumar P, Duhoo Y, Dornfeld LJ, Dubreuil B, Georgeon S, Ovchinnikov S, Woolfson DN, Correia BE, Dey S, Levy ED. Schweke H, et al. Among authors: ovchinnikov s. Cell. 2024 Feb 15;187(4):999-1010.e15. doi: 10.1016/j.cell.2024.01.022. Epub 2024 Feb 6. Cell. 2024. PMID: 38325366 Free article.
Computational design of soluble functional analogues of integral membrane proteins.
Goverde CA, Pacesa M, Goldbach N, Dornfeld LJ, Balbi PEM, Georgeon S, Rosset S, Kapoor S, Choudhury J, Dauparas J, Schellhaas C, Kozlov S, Baker D, Ovchinnikov S, Vecchio AJ, Correia BE. Goverde CA, et al. Among authors: ovchinnikov s. bioRxiv [Preprint]. 2024 Mar 7:2023.05.09.540044. doi: 10.1101/2023.05.09.540044. bioRxiv. 2024. PMID: 38496615 Free PMC article. Preprint.
Predicting multiple conformations via sequence clustering and AlphaFold2.
Wayment-Steele HK, Ojoawo A, Otten R, Apitz JM, Pitsawong W, Hömberger M, Ovchinnikov S, Colwell L, Kern D. Wayment-Steele HK, et al. Among authors: ovchinnikov s. Nature. 2024 Jan;625(7996):832-839. doi: 10.1038/s41586-023-06832-9. Epub 2023 Nov 13. Nature. 2024. PMID: 37956700 Free PMC article.
Unraveling the functional dark matter through global metagenomics.
Pavlopoulos GA, Baltoumas FA, Liu S, Selvitopi O, Camargo AP, Nayfach S, Azad A, Roux S, Call L, Ivanova NN, Chen IM, Paez-Espino D, Karatzas E; Novel Metagenome Protein Families Consortium; Iliopoulos I, Konstantinidis K, Tiedje JM, Pett-Ridge J, Baker D, Visel A, Ouzounis CA, Ovchinnikov S, Buluç A, Kyrpides NC. Pavlopoulos GA, et al. Among authors: ovchinnikov s. Nature. 2023 Oct;622(7983):594-602. doi: 10.1038/s41586-023-06583-7. Epub 2023 Oct 11. Nature. 2023. PMID: 37821698 Free PMC article.
116 results