Oun A - Search Results

1

LRRK2 protects immune cells against erastin-induced ferroptosis.

Oun A, Soliman A, Trombetta-Lima M, Tzepapadaki A, Tsagkari D, Kortholt A, Dolga AM. Oun A, et al. Neurobiol Dis. 2022 Dec;175:105917. doi: 10.1016/j.nbd.2022.105917. Epub 2022 Nov 3. Neurobiol Dis. 2022. PMID: 36336242 Free article.

2

Linalool attenuates oxidative stress and mitochondrial dysfunction mediated by glutamate and NMDA toxicity.

Sabogal-Guáqueta AM, Hobbie F, Keerthi A, Oun A, Kortholt A, Boddeke E, Dolga A. Sabogal-Guáqueta AM, et al. Among authors: oun a. Biomed Pharmacother. 2019 Oct;118:109295. doi: 10.1016/j.biopha.2019.109295. Epub 2019 Sep 6. Biomed Pharmacother. 2019. PMID: 31545255 Free article.

3

Protective effect of metformin against palmitate-induced hepatic cell death.

Geng Y, Hernández Villanueva A, Oun A, Buist-Homan M, Blokzijl H, Faber KN, Dolga A, Moshage H. Geng Y, et al. Among authors: oun a. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165621. doi: 10.1016/j.bbadis.2019.165621. Epub 2019 Nov 29. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31786336 Free article.

4

The tale of proteolysis targeting chimeras (PROTACs) for Leucine-Rich Repeat Kinase 2 (LRRK2).

Konstantinidou M, Oun A, Pathak P, Zhang B, Wang Z, Ter Brake F, Dolga AM, Kortholt A, Dömling A. Konstantinidou M, et al. Among authors: oun a. ChemMedChem. 2021 Mar 18;16(6):959-965. doi: 10.1002/cmdc.202000872. Epub 2020 Dec 29. ChemMedChem. 2021. PMID: 33278061 Free PMC article.

5

A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity.

Rosenbusch KE, Oun A, Sanislav O, Lay ST, Keizer-Gunnink I, Annesley SJ, Fisher PR, Dolga AM, Kortholt A. Rosenbusch KE, et al. Among authors: oun a. Front Cell Dev Biol. 2021 Sep 8;9:734554. doi: 10.3389/fcell.2021.734554. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34568343 Free PMC article.

6

Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity.

Musheshe N, Oun A, Sabogal-Guáqueta AM, Trombetta-Lima M, Mitchel SC, Adzemovic A, Speek O, Morra F, van der Veen CHJT, Lezoualc'h F, Cheng X, Schmidt M, Dolga AM. Musheshe N, et al. Among authors: oun a. Antioxidants (Basel). 2022 Feb 4;11(2):314. doi: 10.3390/antiox11020314. Antioxidants (Basel). 2022. PMID: 35204198 Free PMC article.

7

Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.

Singh RK, Soliman A, Guaitoli G, Störmer E, von Zweydorf F, Dal Maso T, Oun A, Van Rillaer L, Schmidt SH, Chatterjee D, David JA, Pardon E, Schwartz TU, Knapp S, Kennedy EJ, Steyaert J, Herberg FW, Kortholt A, Gloeckner CJ, Versées W. Singh RK, et al. Among authors: oun a. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2112712119. doi: 10.1073/pnas.2112712119. Proc Natl Acad Sci U S A. 2022. PMID: 35217606 Free PMC article.

8

[No title available]

[No authors listed] [No authors listed] PMID: 35555931

9

The multifaceted role of LRRK2 in Parkinson's disease: From human iPSC to organoids.

Oun A, Sabogal-Guaqueta AM, Galuh S, Alexander A, Kortholt A, Dolga AM. Oun A, et al. Neurobiol Dis. 2022 Oct 15;173:105837. doi: 10.1016/j.nbd.2022.105837. Epub 2022 Aug 11. Neurobiol Dis. 2022. PMID: 35963526 Free article. Review.

10

Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages.

Oun A, Hoeksema E, Soliman A, Brouwer F, García-Reyes F, Pots H, Trombetta-Lima M, Kortholt A, Dolga AM. Oun A, et al. Int J Mol Sci. 2023 Jan 13;24(2):1644. doi: 10.3390/ijms24021644. Int J Mol Sci. 2023. PMID: 36675159 Free PMC article.

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