Oumata N - Search Results

1

Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease?

Hochard A, Oumata N, Bettayeb K, Gloulou O, Fant X, Durieu E, Buron N, Porceddu M, Borgne-Sanchez A, Galons H, Flajolet M, Meijer L. Hochard A, et al. Among authors: oumata n. J Alzheimers Dis. 2013;35(1):107-20. doi: 10.3233/JAD-121777. J Alzheimers Dis. 2013. PMID: 23364140 Free PMC article.

2

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases.

Bettayeb K, Oumata N, Echalier A, Ferandin Y, Endicott JA, Galons H, Meijer L. Bettayeb K, et al. Among authors: oumata n. Oncogene. 2008 Oct 2;27(44):5797-807. doi: 10.1038/onc.2008.191. Epub 2008 Jun 23. Oncogene. 2008. PMID: 18574471

3

Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.

Oumata N, Bettayeb K, Ferandin Y, Demange L, Lopez-Giral A, Goddard ML, Myrianthopoulos V, Mikros E, Flajolet M, Greengard P, Meijer L, Galons H. Oumata N, et al. J Med Chem. 2008 Sep 11;51(17):5229-42. doi: 10.1021/jm800109e. Epub 2008 Aug 13. J Med Chem. 2008. PMID: 18698753

4

Cyclin-dependent kinase inhibitors: a survey of recent patent literature.

Galons H, Oumata N, Meijer L. Galons H, et al. Among authors: oumata n. Expert Opin Ther Pat. 2010 Mar;20(3):377-404. doi: 10.1517/13543770903524284. Expert Opin Ther Pat. 2010. PMID: 20180621 Review.

5

Targeting low molecular weight cyclin E (LMW-E) in breast cancer.

Nanos-Webb A, Jabbour NA, Multani AS, Wingate H, Oumata N, Galons H, Joseph B, Meijer L, Hunt KK, Keyomarsi K. Nanos-Webb A, et al. Among authors: oumata n. Breast Cancer Res Treat. 2012 Apr;132(2):575-88. doi: 10.1007/s10549-011-1638-4. Epub 2011 Jun 22. Breast Cancer Res Treat. 2012. PMID: 21695458 Free PMC article.

6

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells.

Bettayeb K, Baunbæk D, Delehouze C, Loaëc N, Hole AJ, Baumli S, Endicott JA, Douc-Rasy S, Bénard J, Oumata N, Galons H, Meijer L. Bettayeb K, et al. Among authors: oumata n. Genes Cancer. 2010 Apr;1(4):369-80. doi: 10.1177/1947601910369817. Genes Cancer. 2010. PMID: 21779453 Free PMC article.

7

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.

Bettayeb K, Oumata N, Zhang Y, Luo W, Bustos V, Galons H, Greengard P, Meijer L, Flajolet M. Bettayeb K, et al. Among authors: oumata n. FASEB J. 2012 Dec;26(12):5115-23. doi: 10.1096/fj.12-212985. Epub 2012 Sep 12. FASEB J. 2012. PMID: 22972917 Free PMC article.

8

Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors.

N'gompaza-Diarra J, Bettayeb K, Gresh N, Meijer L, Oumata N. N'gompaza-Diarra J, et al. Among authors: oumata n. Eur J Med Chem. 2012 Oct;56:210-6. doi: 10.1016/j.ejmech.2012.08.033. Epub 2012 Sep 1. Eur J Med Chem. 2012. PMID: 22982525

9

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.

Bukanov NO, Moreno SE, Natoli TA, Rogers KA, Smith LA, Ledbetter SR, Oumata N, Galons H, Meijer L, Ibraghimov-Beskrovnaya O. Bukanov NO, et al. Among authors: oumata n. Cell Cycle. 2012 Nov 1;11(21):4040-6. doi: 10.4161/cc.22375. Epub 2012 Oct 3. Cell Cycle. 2012. PMID: 23032260 Free PMC article.

10

Inhibition of NF-κB-mediated signaling by the cyclin-dependent kinase inhibitor CR8 overcomes prosurvival stimuli to induce apoptosis in chronic lymphocytic leukemia cells.

Cosimo E, McCaig AM, Carter-Brzezinski LJ, Wheadon H, Leach MT, Le Ster K, Berthou C, Durieu E, Oumata N, Galons H, Meijer L, Michie AM. Cosimo E, et al. Among authors: oumata n. Clin Cancer Res. 2013 May 1;19(9):2393-405. doi: 10.1158/1078-0432.CCR-12-2170. Epub 2013 Mar 26. Clin Cancer Res. 2013. PMID: 23532892

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