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Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis.
J Pathol. 2023 Jun;260(2):112-123. doi: 10.1002/path.6066. Epub 2023 Mar 28.
J Pathol. 2023.
PMID: 36807305
The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma.
Faict S, Oudaert I, D'Auria L, Dehairs J, Maes K, Vlummens P, De Veirman K, De Bruyne E, Fostier K, Vande Broek I, Schots R, Vanderkerken K, Swinnen JV, Menu E.
Faict S, et al. Among authors: oudaert i.
Cancers (Basel). 2019 Nov 20;11(12):1823. doi: 10.3390/cancers11121823.
Cancers (Basel). 2019.
PMID: 31756922
Free PMC article.
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Targeting coenzyme Q10 synthesis overcomes bortezomib resistance in multiple myeloma.
Zaal EA, de Grooth HJ, Oudaert I, Langerhorst P, Levantovsky S, van Slobbe GJJ, Jansen JWA, Menu E, Wu W, Berkers CR.
Zaal EA, et al. Among authors: oudaert i.
Mol Omics. 2022 Jan 17;18(1):19-30. doi: 10.1039/d1mo00106j.
Mol Omics. 2022.
PMID: 34879122
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Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis.
Oudaert I, Satilmis H, Vlummens P, De Brouwer W, Maes A, Hose D, De Bruyne E, Ghesquière B, Vanderkerken K, De Veirman K, Menu E.
Oudaert I, et al.
J Exp Clin Cancer Res. 2022 Feb 1;41(1):45. doi: 10.1186/s13046-022-02250-3.
J Exp Clin Cancer Res. 2022.
PMID: 35105345
Free PMC article.
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System Xc- inhibition blocks bone marrow-multiple myeloma exosomal crosstalk, thereby countering bortezomib resistance.
Wang F, Oudaert I, Tu C, Maes A, Van der Vreken A, Vlummens P, De Bruyne E, De Veirman K, Wang Y, Fan R, Massie A, Vanderkerken K, Shang P, Menu E.
Wang F, et al. Among authors: oudaert i.
Cancer Lett. 2022 Jun 1;535:215649. doi: 10.1016/j.canlet.2022.215649. Epub 2022 Mar 18.
Cancer Lett. 2022.
PMID: 35315341
Free article.
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Metabolic cross-talk within the bone marrow milieu: focus on multiple myeloma.
Oudaert I, Van der Vreken A, Maes A, De Bruyne E, De Veirman K, Vanderkerken K, Menu E.
Oudaert I, et al.
Exp Hematol Oncol. 2022 Sep 1;11(1):49. doi: 10.1186/s40164-022-00303-z.
Exp Hematol Oncol. 2022.
PMID: 36050788
Free PMC article.
Review.
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Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.
Satilmis H, Verheye E, Vlummens P, Oudaert I, Vandewalle N, Fan R, Knight JM, De Beule N, Ates G, Massie A, Moreaux J, Maes A, De Bruyne E, Vanderkerken K, Menu E, Sloan EK, De Veirman K.
Satilmis H, et al. Among authors: oudaert i.
J Pathol. 2023 Jan;259(1):69-80. doi: 10.1002/path.6020. Epub 2022 Nov 22.
J Pathol. 2023.
PMID: 36245401
Free PMC article.
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Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer.
Kerkhove L, Geirnaert F, Rifi AL, Law KL, Gutiérrez A, Oudaert I, Corbet C, Gevaert T, Dufait I, De Ridder M.
Kerkhove L, et al. Among authors: oudaert i.
Cancers (Basel). 2023 Apr 18;15(8):2363. doi: 10.3390/cancers15082363.
Cancers (Basel). 2023.
PMID: 37190291
Free PMC article.
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