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210 results

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Page 1
Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts.
Bian B, Bigonnet M, Gayet O, Loncle C, Maignan A, Gilabert M, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, Poizat F, Nicolle R, Blum Y, Marisa L, Rubis M, Raoul JL, Bradner JE, Qi J, Lomberk G, Urrutia R, Saul A, Dusetti N, Iovanna J. Bian B, et al. Among authors: ouaissi m. EMBO Mol Med. 2017 Apr;9(4):482-497. doi: 10.15252/emmm.201606975. EMBO Mol Med. 2017. PMID: 28275007 Free PMC article.
Transcriptomic analysis predicts survival and sensitivity to anticancer drugs of patients with a pancreatic adenocarcinoma.
Duconseil P, Gilabert M, Gayet O, Loncle C, Moutardier V, Turrini O, Calvo E, Ewald J, Giovannini M, Gasmi M, Bories E, Barthet M, Ouaissi M, Goncalves A, Poizat F, Raoul JL, Secq V, Garcia S, Viens P, Iovanna J, Dusetti N. Duconseil P, et al. Among authors: ouaissi m. Am J Pathol. 2015 Apr;185(4):1022-32. doi: 10.1016/j.ajpath.2014.11.029. Epub 2015 Mar 9. Am J Pathol. 2015. PMID: 25765988 Free article.
A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT.
Barraud M, Garnier J, Loncle C, Gayet O, Lequeue C, Vasseur S, Bian B, Duconseil P, Gilabert M, Bigonnet M, Maignan A, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, Poizat F, Guibert N, Iovanna J, Dusetti N. Barraud M, et al. Among authors: ouaissi m. Oncotarget. 2016 Aug 16;7(33):53783-53796. doi: 10.18632/oncotarget.10776. Oncotarget. 2016. PMID: 27462772 Free PMC article.
Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts.
Nicolle R, Blum Y, Marisa L, Loncle C, Gayet O, Moutardier V, Turrini O, Giovannini M, Bian B, Bigonnet M, Rubis M, Elarouci N, Armenoult L, Ayadi M, Duconseil P, Gasmi M, Ouaissi M, Maignan A, Lomberk G, Boher JM, Ewald J, Bories E, Garnier J, Goncalves A, Poizat F, Raoul JL, Secq V, Garcia S, Grandval P, Barraud-Blanc M, Norguet E, Gilabert M, Delpero JR, Roques J, Calvo E, Guillaumond F, Vasseur S, Urrutia R, de Reyniès A, Dusetti N, Iovanna J. Nicolle R, et al. Among authors: ouaissi m. Cell Rep. 2017 Nov 28;21(9):2458-2470. doi: 10.1016/j.celrep.2017.11.003. Cell Rep. 2017. PMID: 29186684 Free PMC article.
A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor.
Gayet O, Loncle C, Duconseil P, Gilabert M, Lopez MB, Moutardier V, Turrini O, Calvo E, Ewald J, Giovannini M, Gasmi M, Bories E, Barthet M, Ouaissi M, Goncalves A, Poizat F, Raoul JL, Secq V, Garcia S, Viens P, Dusetti N, Iovanna J. Gayet O, et al. Among authors: ouaissi m. Oncotarget. 2015 Jan 20;6(2):746-54. doi: 10.18632/oncotarget.2685. Oncotarget. 2015. PMID: 25481873 Free PMC article.
Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma.
Molejon MI, Tellechea JI, Loncle C, Gayet O, Gilabert M, Duconseil P, Lopez-Millan MB, Moutardier V, Gasmi M, Garcia S, Turrini O, Ouaissi M, Poizat F, Dusetti N, Iovanna J. Molejon MI, et al. Among authors: ouaissi m. Oncotarget. 2015 Apr 10;6(10):7408-23. doi: 10.18632/oncotarget.3510. Oncotarget. 2015. PMID: 25797268 Free PMC article.
Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling.
Secq V, Leca J, Bressy C, Guillaumond F, Skrobuk P, Nigri J, Lac S, Lavaut MN, Bui TT, Thakur AK, Callizot N, Steinschneider R, Berthezene P, Dusetti N, Ouaissi M, Moutardier V, Calvo E, Bousquet C, Garcia S, Bidaut G, Vasseur S, Iovanna JL, Tomasini R. Secq V, et al. Among authors: ouaissi m. Cell Death Dis. 2015 Jan 15;6(1):e1592. doi: 10.1038/cddis.2014.557. Cell Death Dis. 2015. PMID: 25590802 Free PMC article.
Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, Lac S, Borge L, Roques J, Gayet O, Pinault M, Guimaraes C, Nigri J, Loncle C, Lavaut MN, Garcia S, Tailleux A, Staels B, Calvo E, Tomasini R, Iovanna JL, Vasseur S. Guillaumond F, et al. Among authors: ouaissi m. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2473-8. doi: 10.1073/pnas.1421601112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675507 Free PMC article.
Further characterization of HDAC and SIRT gene expression patterns in pancreatic cancer and their relation to disease outcome.
Ouaïssi M, Silvy F, Loncle C, Ferraz da Silva D, Martins Abreu C, Martinez E, Berthézene P, Cadra S, Le Treut YP, Hardwigsen J, Sastre B, Sielezneff I, Benkoel L, Delgrande J, Ouaissi A, Iovanna J, Lombardo D, Mas E. Ouaïssi M, et al. Among authors: ouaissi a. PLoS One. 2014 Oct 2;9(9):e108520. doi: 10.1371/journal.pone.0108520. eCollection 2014. PLoS One. 2014. PMID: 25275504 Free PMC article.
210 results