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Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement.
Vasta JD, Corona CR, Wilkinson J, Zimprich CA, Hartnett JR, Ingold MR, Zimmerman K, Machleidt T, Kirkland TA, Huwiler KG, Ohana RF, Slater M, Otto P, Cong M, Wells CI, Berger BT, Hanke T, Glas C, Ding K, Drewry DH, Huber KVM, Willson TM, Knapp S, Müller S, Meisenheimer PL, Fan F, Wood KV, Robers MB. Vasta JD, et al. Among authors: otto p. Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. doi: 10.1016/j.chembiol.2017.10.010. Epub 2017 Nov 22. Cell Chem Biol. 2018. PMID: 29174542 Free PMC article.
NanoBRET--A Novel BRET Platform for the Analysis of Protein-Protein Interactions.
Machleidt T, Woodroofe CC, Schwinn MK, Méndez J, Robers MB, Zimmerman K, Otto P, Daniels DL, Kirkland TA, Wood KV. Machleidt T, et al. Among authors: otto p. ACS Chem Biol. 2015 Aug 21;10(8):1797-804. doi: 10.1021/acschembio.5b00143. Epub 2015 Jun 9. ACS Chem Biol. 2015. PMID: 26006698 Free article.
Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate.
Hall MP, Unch J, Binkowski BF, Valley MP, Butler BL, Wood MG, Otto P, Zimmerman K, Vidugiris G, Machleidt T, Robers MB, Benink HA, Eggers CT, Slater MR, Meisenheimer PL, Klaubert DH, Fan F, Encell LP, Wood KV. Hall MP, et al. Among authors: otto p. ACS Chem Biol. 2012 Nov 16;7(11):1848-57. doi: 10.1021/cb3002478. Epub 2012 Aug 30. ACS Chem Biol. 2012. PMID: 22894855 Free PMC article.
HaloTag: a novel protein labeling technology for cell imaging and protein analysis.
Los GV, Encell LP, McDougall MG, Hartzell DD, Karassina N, Zimprich C, Wood MG, Learish R, Ohana RF, Urh M, Simpson D, Mendez J, Zimmerman K, Otto P, Vidugiris G, Zhu J, Darzins A, Klaubert DH, Bulleit RF, Wood KV. Los GV, et al. Among authors: otto p. ACS Chem Biol. 2008 Jun 20;3(6):373-82. doi: 10.1021/cb800025k. ACS Chem Biol. 2008. PMID: 18533659
Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands.
Encell LP, Friedman Ohana R, Zimmerman K, Otto P, Vidugiris G, Wood MG, Los GV, McDougall MG, Zimprich C, Karassina N, Learish RD, Hurst R, Hartnett J, Wheeler S, Stecha P, English J, Zhao K, Mendez J, Benink HA, Murphy N, Daniels DL, Slater MR, Urh M, Darzins A, Klaubert DH, Bulleit RF, Wood KV. Encell LP, et al. Among authors: otto p. Curr Chem Genomics. 2012;6:55-71. doi: 10.2174/1875397301206010055. Epub 2012 Oct 5. Curr Chem Genomics. 2012. PMID: 23248739 Free PMC article.
A luminescent biosensor with increased dynamic range for intracellular cAMP.
Binkowski BF, Butler BL, Stecha PF, Eggers CT, Otto P, Zimmerman K, Vidugiris G, Wood MG, Encell LP, Fan F, Wood KV. Binkowski BF, et al. Among authors: otto p. ACS Chem Biol. 2011 Nov 18;6(11):1193-7. doi: 10.1021/cb200248h. Epub 2011 Sep 22. ACS Chem Biol. 2011. PMID: 21932825
Imaging proteolytic activity in live cells and animal models.
Galbán S, Jeon YH, Bowman BM, Stevenson J, Sebolt KA, Sharkey LM, Lafferty M, Hoff BA, Butler BL, Wigdal SS, Binkowski BF, Otto P, Zimmerman K, Vidugiris G, Encell LP, Fan F, Wood KV, Galbán CJ, Ross BD, Rehemtulla A. Galbán S, et al. Among authors: otto p. PLoS One. 2013 Jun 11;8(6):e66248. doi: 10.1371/journal.pone.0066248. Print 2013. PLoS One. 2013. PMID: 23776643 Free PMC article.
346 results