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971 results

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Page 1
LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.
Loesche C, Picard D, Van Hoorick B, Schuhmann I, Jäger P, Klein K, Schuhler C, Thoma G, Markert C, Poller B, Zamurovic N, Weiss HM, Otto H, Fink M, Röhn TA. Loesche C, et al. Among authors: otto h. Clin Transl Sci. 2024 Feb;17(2):e13724. doi: 10.1111/cts.13724. Clin Transl Sci. 2024. PMID: 38407540 Free PMC article. Clinical Trial.
Randomized, double-blind, multicenter study to evaluate efficacy, safety, tolerability, and immunogenicity between AVT04 and the reference product ustekinumab in patients with moderate-to-severe chronic plaque psoriasis.
Feldman SR, Reznichenko N, Berti F, Duijzings P, Ruffieux R, Otto H, Haliduola HN, Leutz S, Stroissnig H. Feldman SR, et al. Among authors: otto h. Expert Opin Biol Ther. 2023 Jul-Dec;23(8):759-771. doi: 10.1080/14712598.2023.2235263. Epub 2023 Jul 12. Expert Opin Biol Ther. 2023. PMID: 37435850 Clinical Trial.
Using archived and biocollection samples towards deciphering the DNA virus diversity associated with rodent species in the families cricetidae and heteromyidae.
Lund MC, Larsen BB, Rowsey DM, Otto HW, Gryseels S, Kraberger S, Custer JM, Steger L, Yule KM, Harris RE, Worobey M, Van Doorslaer K, Upham NS, Varsani A. Lund MC, et al. Among authors: otto hw. Virology. 2023 Aug;585:42-60. doi: 10.1016/j.virol.2023.05.006. Epub 2023 Jun 1. Virology. 2023. PMID: 37276766
A randomized, double-blind, 3-arm, parallel study assessing the pharmacokinetics, safety, tolerability and immunogenicity of AVT04, an ustekinumab candidate biosimilar, in healthy adults.
Wynne C, Hamilton P, McLendon K, Stroissnig H, Smith M, Duijzings P, Ruffieux R, Otto H, Sattar A, Haliduola HN, Leutz S, Berti F. Wynne C, et al. Among authors: otto h. Expert Opin Investig Drugs. 2023 May;32(5):417-427. doi: 10.1080/13543784.2023.2215426. Epub 2023 May 23. Expert Opin Investig Drugs. 2023. PMID: 37212315 Clinical Trial.
Assessing the Interchangeability of AVT02 and Humira® in Participants with Moderate‑to‑Severe Chronic Plaque Psoriasis: Pharmacokinetics, Efficacy, Safety, and Immunogenicity Results from a Multicenter, Double-Blind, Randomized, Parallel-Group Study.
Feldman SR, Kay R, Reznichenko N, Sobierska J, Dias R, Otto H, Haliduola HN, Sattar A, Ruffieux R, Stroissnig H, Berti F. Feldman SR, et al. Among authors: otto h. BioDrugs. 2023 Jul;37(4):551-567. doi: 10.1007/s40259-023-00600-x. Epub 2023 May 19. BioDrugs. 2023. PMID: 37204631 Free PMC article. Clinical Trial.
Diverse DNA virus genomes identified in fecal samples of Mexican free-tailed bats (Tadarida brasiliensis) captured in Chiricahua Mountains of southeast Arizona (USA).
Harding C, Larsen BB, Otto HW, Potticary AL, Kraberger S, Custer JM, Suazo C, Upham NS, Worobey M, Van Doorslaer K, Varsani A. Harding C, et al. Among authors: otto hw. Virology. 2023 Mar;580:98-111. doi: 10.1016/j.virol.2023.02.004. Epub 2023 Feb 12. Virology. 2023. PMID: 36801670 Free article.
A localized view on molecular dissociation via electron-ion partial covariance.
Allum F, Music V, Inhester L, Boll R, Erk B, Schmidt P, Baumann TM, Brenner G, Burt M, Demekhin PV, Dörner S, Ehresmann A, Galler A, Grychtol P, Heathcote D, Kargin D, Larsson M, Lee JWL, Li Z, Manschwetus B, Marder L, Mason R, Meyer M, Otto H, Passow C, Pietschnig R, Ramm D, Schubert K, Schwob L, Thomas RD, Vallance C, Vidanović I, von Korff Schmising C, Wagner R, Walter P, Zhaunerchyk V, Rolles D, Bari S, Brouard M, Ilchen M. Allum F, et al. Among authors: otto h. Commun Chem. 2022 Mar 28;5(1):42. doi: 10.1038/s42004-022-00656-w. Commun Chem. 2022. PMID: 36697752 Free PMC article.
971 results