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ProstaTrend-A Multivariable Prognostic RNA Expression Score for Aggressive Prostate Cancer.
Kreuz M, Otto DJ, Fuessel S, Blumert C, Bertram C, Bartsch S, Loeffler D, Puppel SH, Rade M, Buschmann T, Christ S, Erdmann K, Friedrich M, Froehner M, Muders MH, Schreiber S, Specht M, Toma MI, Benigni F, Freschi M, Gandaglia G, Briganti A, Baretton GB, Loeffler M, Hackermüller J, Reiche K, Wirth M, Horn F. Kreuz M, et al. Among authors: otto dj. Eur Urol. 2020 Sep;78(3):452-459. doi: 10.1016/j.eururo.2020.06.001. Epub 2020 Jul 4. Eur Urol. 2020. PMID: 32631745
Characterization and evaluation of gene fusions as a measure of genetic instability and disease prognosis in prostate cancer.
Schimmelpfennig C, Rade M, Füssel S, Löffler D, Blumert C, Bertram C, Borkowetz A, Otto DJ, Puppel SH, Hönscheid P, Sommer U, Baretton GB, Köhl U, Wirth M, Thomas C, Horn F, Kreuz M, Reiche K. Schimmelpfennig C, et al. Among authors: otto dj. BMC Cancer. 2023 Jun 22;23(1):575. doi: 10.1186/s12885-023-11019-6. BMC Cancer. 2023. PMID: 37349736 Free PMC article.
A reliable transcriptomic risk-score applicable to formalin-fixed paraffin-embedded biopsies improves outcome prediction in localized prostate cancer.
Rade M, Kreuz M, Borkowetz A, Sommer U, Blumert C, Füssel S, Bertram C, Löffler D, Otto DJ, Wöller LA, Schimmelpfennig C, Köhl U, Gottschling AC, Hönscheid P, Baretton GB, Wirth M, Thomas C, Horn F, Reiche K. Rade M, et al. Among authors: otto dj. Mol Med. 2024 Feb 1;30(1):19. doi: 10.1186/s10020-024-00789-9. Mol Med. 2024. PMID: 38302875 Free PMC article.
Defining and benchmarking open problems in single-cell analysis.
Luecken MD, Gigante S, Burkhardt DB, Cannoodt R, Strobl DC, Markov NS, Zappia L, Palla G, Lewis W, Dimitrov D, Vinyard ME, Magruder DS, Andersson A, Dann E, Qin Q, Otto DJ, Klein M, Botvinnik OB, Deconinck L, Waldrant K; Open Problems Jamboree Members; Bloom JM, Pisco AO, Saez-Rodriguez J, Wulsin D, Pinello L, Saeys Y, Theis FJ, Krishnaswamy S. Luecken MD, et al. Among authors: otto dj. Res Sq [Preprint]. 2024 Apr 4:rs.3.rs-4181617. doi: 10.21203/rs.3.rs-4181617/v1. Res Sq. 2024. PMID: 38645152 Free PMC article. Preprint.
KMT2A oncoproteins induce epigenetic resistance to targeted therapies.
Janssens DH, Duran M, Otto DJ, Kirkey D, Yi JS, Meshinchi S, Sarthy JF, Ahmad K, Henikoff S. Janssens DH, et al. Among authors: otto dj. bioRxiv [Preprint]. 2023 Dec 30:2023.12.29.573681. doi: 10.1101/2023.12.29.573681. bioRxiv. 2023. PMID: 38234854 Free PMC article. Preprint.