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Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit proteins.
Findlay-Wilson S, Easterbrook L, Smith S, Pope N, Humphries G, Schuhmann H, Ngabo D, Rayner E, Otter AD, Coleman T, Hicks B, Graham VA, Halkerston R, Apostolakis K, Taylor S, Fotheringham S, Horton A, Tree JA, Wand M, Hewson R, Dowall SD. Findlay-Wilson S, et al. Among authors: otter ad. Antiviral Res. 2022 Jul;203:105332. doi: 10.1016/j.antiviral.2022.105332. Epub 2022 May 6. Antiviral Res. 2022. PMID: 35533779 Free PMC article.
Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection.
Manisty C, Treibel TA, Jensen M, Semper A, Joy G, Gupta RK, Cutino-Moguel T, Andiapen M, Jones J, Taylor S, Otter A, Pade C, Gibbons J, Lee J, Bacon J, Thomas S, Moon C, Jones M, Williams D, Lambourne J, Fontana M, Altmann DM, Boyton R, Maini M, McKnight A, Chain B, Noursadeghi M, Moon JC. Manisty C, et al. EBioMedicine. 2021 Mar;65:103259. doi: 10.1016/j.ebiom.2021.103259. Epub 2021 Mar 2. EBioMedicine. 2021. PMID: 33662833 Free PMC article.
Comparability of six different immunoassays measuring SARS-CoV-2 antibodies with neutralizing antibody levels in convalescent plasma: From utility to prediction.
Lamikanra A, Nguyen D, Simmonds P, Williams S, Bentley EM, Rowe C, Otter AD, Brooks T, Gilmour K, Mai A, Dadhra J, Csatari M, Ziyenge S, Oliveira M, Ploeg R, Tsang P, Zambon M, Gopal R, Xiao JH, Townsend A, Roberts D, Harvala H. Lamikanra A, et al. Among authors: otter ad. Transfusion. 2021 Oct;61(10):2837-2843. doi: 10.1111/trf.16600. Epub 2021 Aug 17. Transfusion. 2021. PMID: 34342366 Free PMC article.
mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant.
Parry H, Tut G, Bruton R, Faustini S, Stephens C, Saunders P, Bentley C, Hilyard K, Brown K, Amirthalingam G, Charlton S, Leung S, Chiplin E, Coombes NS, Bewley KR, Penn EJ, Rowe C, Otter A, Watts R, D'Arcangelo S, Hallis B, Makin A, Richter A, Zuo J, Moss P. Parry H, et al. Elife. 2021 Sep 29;10:e69375. doi: 10.7554/eLife.69375. Elife. 2021. PMID: 34586068 Free PMC article.
Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants.
Reynolds CJ, Gibbons JM, Pade C, Lin KM, Sandoval DM, Pieper F, Butler DK, Liu S, Otter AD, Joy G, Menacho K, Fontana M, Smit A, Kele B, Cutino-Moguel T, Maini MK, Noursadeghi M; COVIDsortium Immune Correlates Network‡; Brooks T, Semper A, Manisty C, Treibel TA, Moon JC; COVIDsortium Investigators‡; McKnight Á, Altmann DM, Boyton RJ. Reynolds CJ, et al. Among authors: otter ad. Science. 2022 Jan 14;375(6577):183-192. doi: 10.1126/science.abm0811. Epub 2021 Dec 2. Science. 2022. PMID: 34855510 Free PMC article.
HLA-DR polymorphism in SARS-CoV-2 infection and susceptibility to symptomatic COVID-19.
Astbury S, Reynolds CJ, Butler DK, Muñoz-Sandoval DC, Lin KM, Pieper FP, Otter A, Kouraki A, Cusin L, Nightingale J, Vijay A, Craxford S, Aithal GP, Tighe PJ, Gibbons JM, Pade C, Joy G, Maini M, Chain B, Semper A, Brooks T, Ollivere BJ, McKnight Á, Noursadeghi M, Treibel TA, Manisty C, Moon JC; COVIDsortium Investigators*; Valdes AM, Boyton RJ, Altmann DM. Astbury S, et al. Immunology. 2022 May;166(1):68-77. doi: 10.1111/imm.13450. Epub 2022 Mar 8. Immunology. 2022. PMID: 35156709 Free PMC article.
Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection.
Hall V, Foulkes S, Insalata F, Kirwan P, Saei A, Atti A, Wellington E, Khawam J, Munro K, Cole M, Tranquillini C, Taylor-Kerr A, Hettiarachchi N, Calbraith D, Sajedi N, Milligan I, Themistocleous Y, Corrigan D, Cromey L, Price L, Stewart S, de Lacy E, Norman C, Linley E, Otter AD, Semper A, Hewson J, D'Arcangelo S, Chand M, Brown CS, Brooks T, Islam J, Charlett A, Hopkins S; SIREN Study Group. Hall V, et al. Among authors: otter ad. N Engl J Med. 2022 Mar 31;386(13):1207-1220. doi: 10.1056/NEJMoa2118691. Epub 2022 Feb 16. N Engl J Med. 2022. PMID: 35172051 Free PMC article.
Implementation and Extended Evaluation of the Euroimmun Anti-SARS-CoV-2 IgG Assay and Its Contribution to the United Kingdom's COVID-19 Public Health Response.
Otter AD, Bown A, D'Arcangelo S, Bailey D, Semper A, Hewson J, Catton M, Perumal P, Sweed A, McKee DF, Jones J, Harvala H, Lamikanra A, Zambon M, Andrews N, Whitaker H, Linley E, Mentzer AJ, Skelly D, Knight JC, Klenerman P; UKHSA Porton Euroimmun testing group; Amirthalingam G, Taylor S, Rowe C, Vipond R, Brooks T. Otter AD, et al. Microbiol Spectr. 2022 Feb 23;10(1):e0228921. doi: 10.1128/spectrum.02289-21. Epub 2022 Feb 23. Microbiol Spectr. 2022. PMID: 35196807 Free PMC article.
Convalescent plasma donors show enhanced cross-reactive neutralizing antibody response to antigenic variants of SARS-CoV-2 following immunization.
Harvala H, Nguyen D, Simmonds P, Lamikanra AA, Tsang HP, Otter A, Maes P, Webster M, Clarkson A, Kaloyirou F, Hopkins V, Laidlaw SM, Carroll M, Mora A, Griffiths A, MacLennan S, Estcourt L, Roberts DJ. Harvala H, et al. Transfusion. 2022 Jul;62(7):1347-1354. doi: 10.1111/trf.16934. Epub 2022 Jun 2. Transfusion. 2022. PMID: 35588314 Free PMC article.
50 results