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A novel mammalian receptor for the evolutionarily conserved type II GnRH.
Millar R, Lowe S, Conklin D, Pawson A, Maudsley S, Troskie B, Ott T, Millar M, Lincoln G, Sellar R, Faurholm B, Scobie G, Kuestner R, Terasawa E, Katz A. Millar R, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9636-41. doi: 10.1073/pnas.141048498. Epub 2001 Aug 7. Proc Natl Acad Sci U S A. 2001. PMID: 11493674 Free PMC article.
A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants.
Sun YM, Flanagan CA, Illing N, Ott TR, Sellar R, Fromme BJ, Hapgood J, Sharp P, Sealfon SC, Millar RP. Sun YM, et al. Among authors: ott tr. J Biol Chem. 2001 Mar 16;276(11):7754-61. doi: 10.1074/jbc.M009020200. Epub 2000 Dec 8. J Biol Chem. 2001. PMID: 11112780 Free article.
Structural requirements of transmembrane domain 3 for activation by the M1 muscarinic receptor agonists AC-42, AC-260584, clozapine, and N-desmethylclozapine: evidence for three distinct modes of receptor activation.
Spalding TA, Ma JN, Ott TR, Friberg M, Bajpai A, Bradley SR, Davis RE, Brann MR, Burstein ES. Spalding TA, et al. Among authors: ott tr. Mol Pharmacol. 2006 Dec;70(6):1974-83. doi: 10.1124/mol.106.024901. Epub 2006 Sep 7. Mol Pharmacol. 2006. PMID: 16959945
14 results