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Expansion of functional personalized cells with specific transgene combinations.
Lipps C, Klein F, Wahlicht T, Seiffert V, Butueva M, Zauers J, Truschel T, Luckner M, Köster M, MacLeod R, Pezoldt J, Hühn J, Yuan Q, Müller PP, Kempf H, Zweigerdt R, Dittrich-Breiholz O, Pufe T, Beckmann R, Drescher W, Riancho J, Sañudo C, Korff T, Opalka B, Rebmann V, Göthert JR, Alves PM, Ott M, Schucht R, Hauser H, Wirth D, May T. Lipps C, et al. Among authors: ott m. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4. Nat Commun. 2018. PMID: 29520052 Free PMC article.
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice.
Haridass D, Yuan Q, Becker PD, Cantz T, Iken M, Rothe M, Narain N, Bock M, Nörder M, Legrand N, Wedemeyer H, Weijer K, Spits H, Manns MP, Cai J, Deng H, Di Santo JP, Guzman CA, Ott M. Haridass D, et al. Among authors: ott m. Am J Pathol. 2009 Oct;175(4):1483-92. doi: 10.2353/ajpath.2009.090117. Epub 2009 Aug 28. Am J Pathol. 2009. PMID: 19717639 Free PMC article.
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L. Kang TW, et al. Among authors: ott m. Nature. 2011 Nov 9;479(7374):547-51. doi: 10.1038/nature10599. Nature. 2011. PMID: 22080947
Specific gene delivery to liver sinusoidal and artery endothelial cells.
Abel T, El Filali E, Waern J, Schneider IC, Yuan Q, Münch RC, Hick M, Warnecke G, Madrahimov N, Kontermann RE, Schüttrumpf J, Müller UC, Seppen J, Ott M, Buchholz CJ. Abel T, et al. Among authors: ott m. Blood. 2013 Sep 19;122(12):2030-8. doi: 10.1182/blood-2012-11-468579. Epub 2013 Jul 24. Blood. 2013. PMID: 23884859 Free article.
Sustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapy.
Eggenschwiler R, Loya K, Wu G, Sharma AD, Sgodda M, Zychlinski D, Herr C, Steinemann D, Teckman J, Bals R, Ott M, Schambach A, Schöler HR, Cantz T. Eggenschwiler R, et al. Among authors: ott m. Stem Cells Transl Med. 2013 Sep;2(9):641-54. doi: 10.5966/sctm.2013-0017. Epub 2013 Aug 7. Stem Cells Transl Med. 2013. PMID: 23926210 Free PMC article.
Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis.
Song G, Pacher M, Balakrishnan A, Yuan Q, Tsay HC, Yang D, Reetz J, Brandes S, Dai Z, Pützer BM, Araúzo-Bravo MJ, Steinemann D, Luedde T, Schwabe RF, Manns MP, Schöler HR, Schambach A, Cantz T, Ott M, Sharma AD. Song G, et al. Among authors: ott m. Cell Stem Cell. 2016 Jun 2;18(6):797-808. doi: 10.1016/j.stem.2016.01.010. Epub 2016 Feb 25. Cell Stem Cell. 2016. PMID: 26923201 Free article.
MicroRNA-125b-5p mimic inhibits acute liver failure.
Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann JH, Manns MP, Ott M, Cantz T, Sharma AD. Yang D, et al. Among authors: ott m. Nat Commun. 2016 Jun 23;7:11916. doi: 10.1038/ncomms11916. Nat Commun. 2016. PMID: 27336362 Free PMC article.
1,245 results