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The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α.
Chandra V, Ibrahim H, Halliez C, Prasad RB, Vecchio F, Dwivedi OP, Kvist J, Balboa D, Saarimäki-Vire J, Montaser H, Barsby T, Lithovius V, Artner I, Gopalakrishnan S, Groop L, Mallone R, Eizirik DL, Otonkoski T. Chandra V, et al. Among authors: otonkoski t. Nat Commun. 2022 Oct 26;13(1):6363. doi: 10.1038/s41467-022-34069-z. Nat Commun. 2022. PMID: 36289205 Free PMC article.
Activin A and Wnt-dependent specification of human definitive endoderm cells.
Toivonen S, Lundin K, Balboa D, Ustinov J, Tamminen K, Palgi J, Trokovic R, Tuuri T, Otonkoski T. Toivonen S, et al. Among authors: otonkoski t. Exp Cell Res. 2013 Oct 15;319(17):2535-44. doi: 10.1016/j.yexcr.2013.07.007. Epub 2013 Aug 14. Exp Cell Res. 2013. PMID: 23954819
Selective microRNA-Offset RNA expression in human embryonic stem cells.
Asikainen S, Heikkinen L, Juhila J, Holm F, Weltner J, Trokovic R, Mikkola M, Toivonen S, Balboa D, Lampela R, Icay K, Tuuri T, Otonkoski T, Wong G, Hovatta O. Asikainen S, et al. Among authors: otonkoski t. PLoS One. 2015 Mar 30;10(3):e0116668. doi: 10.1371/journal.pone.0116668. eCollection 2015. PLoS One. 2015. PMID: 25822230 Free PMC article.
Human pluripotent stem cell based islet models for diabetes research.
Balboa D, Otonkoski T. Balboa D, et al. Among authors: otonkoski t. Best Pract Res Clin Endocrinol Metab. 2015 Dec;29(6):899-909. doi: 10.1016/j.beem.2015.10.012. Epub 2015 Oct 30. Best Pract Res Clin Endocrinol Metab. 2015. PMID: 26696518 Review.
An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation.
Saarimäki-Vire J, Balboa D, Russell MA, Saarikettu J, Kinnunen M, Keskitalo S, Malhi A, Valensisi C, Andrus C, Eurola S, Grym H, Ustinov J, Wartiovaara K, Hawkins RD, Silvennoinen O, Varjosalo M, Morgan NG, Otonkoski T. Saarimäki-Vire J, et al. Among authors: otonkoski t. Cell Rep. 2017 Apr 11;19(2):281-294. doi: 10.1016/j.celrep.2017.03.055. Cell Rep. 2017. PMID: 28402852 Free article.
215 results