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Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J. Haikala HM, et al. Among authors: otonkoski t. Nat Commun. 2019 Feb 6;10(1):620. doi: 10.1038/s41467-019-08541-2. Nat Commun. 2019. PMID: 30728358 Free PMC article.
Activin A and Wnt-dependent specification of human definitive endoderm cells.
Toivonen S, Lundin K, Balboa D, Ustinov J, Tamminen K, Palgi J, Trokovic R, Tuuri T, Otonkoski T. Toivonen S, et al. Among authors: otonkoski t. Exp Cell Res. 2013 Oct 15;319(17):2535-44. doi: 10.1016/j.yexcr.2013.07.007. Epub 2013 Aug 14. Exp Cell Res. 2013. PMID: 23954819
Human pluripotent stem cell based islet models for diabetes research.
Balboa D, Otonkoski T. Balboa D, et al. Among authors: otonkoski t. Best Pract Res Clin Endocrinol Metab. 2015 Dec;29(6):899-909. doi: 10.1016/j.beem.2015.10.012. Epub 2015 Oct 30. Best Pract Res Clin Endocrinol Metab. 2015. PMID: 26696518 Review.
p73 is required for appropriate BMP-induced mesenchymal-to-epithelial transition during somatic cell reprogramming.
Martin-Lopez M, Maeso-Alonso L, Fuertes-Alvarez S, Balboa D, Rodríguez-Cortez V, Weltner J, Diez-Prieto I, Davis A, Wu Y, Otonkoski T, Flores ER, Menéndez P, Marques MM, Marin MC. Martin-Lopez M, et al. Among authors: otonkoski t. Cell Death Dis. 2017 Sep 7;8(9):e3034. doi: 10.1038/cddis.2017.432. Cell Death Dis. 2017. PMID: 28880267 Free PMC article.
Human pluripotent reprogramming with CRISPR activators.
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutškov K, Jouhilahti EM, Trokovic R, Kere J, Otonkoski T. Weltner J, et al. Among authors: otonkoski t. Nat Commun. 2018 Jul 6;9(1):2643. doi: 10.1038/s41467-018-05067-x. Nat Commun. 2018. PMID: 29980666 Free PMC article.
216 results