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Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.
Bouley R, Kumarasiri M, Peng Z, Otero LH, Song W, Suckow MA, Schroeder VA, Wolter WR, Lastochkin E, Antunes NT, Pi H, Vakulenko S, Hermoso JA, Chang M, Mobashery S. Bouley R, et al. Among authors: otero lh. J Am Chem Soc. 2015 Feb 11;137(5):1738-41. doi: 10.1021/jacs.5b00056. Epub 2015 Feb 2. J Am Chem Soc. 2015. PMID: 25629446 Free PMC article.
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function.
Otero LH, Rojas-Altuve A, Llarrull LI, Carrasco-López C, Kumarasiri M, Lastochkin E, Fishovitz J, Dawley M, Hesek D, Lee M, Johnson JW, Fisher JF, Chang M, Mobashery S, Hermoso JA. Otero LH, et al. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16808-13. doi: 10.1073/pnas.1300118110. Epub 2013 Oct 1. Proc Natl Acad Sci U S A. 2013. PMID: 24085846 Free PMC article.
Structural basis for the broad specificity of a new family of amino-acid racemases.
Espaillat A, Carrasco-López C, Bernardo-García N, Pietrosemoli N, Otero LH, Álvarez L, de Pedro MA, Pazos F, Davis BM, Waldor MK, Hermoso JA, Cava F. Espaillat A, et al. Among authors: otero lh. Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):79-90. doi: 10.1107/S1399004713024838. Epub 2013 Dec 24. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24419381 Free PMC article.
Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif.
Lorenzo R, Defelipe LA, Aliperti L, Niebling S, Custódio TF, Löw C, Schwarz JJ, Remans K, Craig PO, Otero LH, Klinke S, García-Alai M, Sánchez IE, Alonso LG. Lorenzo R, et al. Among authors: otero lh. J Biol Chem. 2021 Oct;297(4):101175. doi: 10.1016/j.jbc.2021.101175. Epub 2021 Sep 7. J Biol Chem. 2021. PMID: 34499924 Free PMC article.
37 results