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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion.
Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM. Hope JL, et al. Among authors: otero dc. Cell Rep. 2023 May 30;42(5):112436. doi: 10.1016/j.celrep.2023.112436. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37115668 Free PMC article.
PSGL-1: A New Player in the Immune Checkpoint Landscape.
Tinoco R, Otero DC, Takahashi AA, Bradley LM. Tinoco R, et al. Among authors: otero dc. Trends Immunol. 2017 May;38(5):323-335. doi: 10.1016/j.it.2017.02.002. Epub 2017 Mar 2. Trends Immunol. 2017. PMID: 28262471 Free PMC article. Review.
MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses.
Hope JL, Zhao M, Stairiker CJ, Kiernan CH, Carey AJ, Mueller YM, van Meurs M, Brouwers-Haspels I, Otero DC, Bae EA, Faso HA, Maas A, de Looper H, Fortina PM, Rigoutsos I, Bradley LM, Erkeland SJ, Katsikis PD. Hope JL, et al. Among authors: otero dc. J Immunol. 2022 Feb 1;208(3):603-617. doi: 10.4049/jimmunol.2000621. Epub 2022 Jan 12. J Immunol. 2022. PMID: 35022277 Free PMC article.
Siah2 control of T-regulatory cells limits anti-tumor immunity.
Scortegagna M, Hockemeyer K, Dolgalev I, Poźniak J, Rambow F, Li Y, Feng Y, Tinoco R, Otero DC, Zhang T, Brown K, Bosenberg M, Bradley LM, Marine JC, Aifantis I, Ronai ZA. Scortegagna M, et al. Among authors: otero dc. Nat Commun. 2020 Jan 7;11(1):99. doi: 10.1038/s41467-019-13826-7. Nat Commun. 2020. PMID: 31911617 Free PMC article.
PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.
Tinoco R, Carrette F, Barraza ML, Otero DC, Magaña J, Bosenberg MW, Swain SL, Bradley LM. Tinoco R, et al. Among authors: otero dc. Immunity. 2016 Jun 21;44(6):1470. doi: 10.1016/j.immuni.2016.05.011. Immunity. 2016. PMID: 27332735 Free article. No abstract available.
25 results