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Quantifying circulating cell-free DNA in humans.
Meddeb R, Dache ZAA, Thezenas S, Otandault A, Tanos R, Pastor B, Sanchez C, Azzi J, Tousch G, Azan S, Mollevi C, Adenis A, El Messaoudi S, Blache P, Thierry AR. Meddeb R, et al. Among authors: otandault a. Sci Rep. 2019 Mar 26;9(1):5220. doi: 10.1038/s41598-019-41593-4. Sci Rep. 2019. PMID: 30914716 Free PMC article. Clinical Trial.
Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer.
Jeitany M, Leroy C, Tosti P, Lafitte M, Le Guet J, Simon V, Bonenfant D, Robert B, Grillet F, Mollevi C, El Messaoudi S, Otandault A, Canterel-Thouennon L, Busson M, Thierry AR, Martineau P, Pannequin J, Roche S, Sirvent A. Jeitany M, et al. Among authors: otandault a. EMBO Mol Med. 2018 Apr;10(4):e7918. doi: 10.15252/emmm.201707918. EMBO Mol Med. 2018. PMID: 29438985 Free PMC article.
Recent advances in circulating nucleic acids in oncology.
Otandault A, Anker P, Al Amir Dache Z, Guillaumon V, Meddeb R, Pastor B, Pisareva E, Sanchez C, Tanos R, Tousch G, Schwarzenbach H, Thierry AR. Otandault A, et al. Ann Oncol. 2019 Mar 1;30(3):374-384. doi: 10.1093/annonc/mdz031. Ann Oncol. 2019. PMID: 30753271 Free article. Review.
Hypoxia differently modulates the release of mitochondrial and nuclear DNA.
Otandault A, Abraham JD, Al Amir Dache Z, Khalyfa A, Jariel-Encontre I, Forné T, Prévostel C, Chouaib S, Gozal D, Thierry AR. Otandault A, et al. Br J Cancer. 2020 Mar;122(5):715-725. doi: 10.1038/s41416-019-0716-y. Epub 2020 Jan 13. Br J Cancer. 2020. PMID: 31929518 Free PMC article.
Blood contains circulating cell-free respiratory competent mitochondria.
Al Amir Dache Z, Otandault A, Tanos R, Pastor B, Meddeb R, Sanchez C, Arena G, Lasorsa L, Bennett A, Grange T, El Messaoudi S, Mazard T, Prevostel C, Thierry AR. Al Amir Dache Z, et al. Among authors: otandault a. FASEB J. 2020 Mar;34(3):3616-3630. doi: 10.1096/fj.201901917RR. Epub 2020 Jan 19. FASEB J. 2020. PMID: 31957088 Free article.
Machine Learning-Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening.
Tanos R, Tosato G, Otandault A, Al Amir Dache Z, Pique Lasorsa L, Tousch G, El Messaoudi S, Meddeb R, Diab Assaf M, Ychou M, Du Manoir S, Pezet D, Gagnière J, Colombo PE, Jacot W, Assénat E, Dupuy M, Adenis A, Mazard T, Mollevi C, Sayagués JM, Colinge J, Thierry AR. Tanos R, et al. Among authors: otandault a. Adv Sci (Weinh). 2020 Jul 29;7(18):2000486. doi: 10.1002/advs.202000486. eCollection 2020 Sep. Adv Sci (Weinh). 2020. PMID: 32999827 Free PMC article.