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Arrestin-1 engineering facilitates complex stabilization with native rhodopsin.
Haider RS, Wilhelm F, Rizk A, Mutt E, Deupi X, Peterhans C, Mühle J, Berger P, Schertler GFX, Standfuss J, Ostermaier MK. Haider RS, et al. Among authors: ostermaier mk. Sci Rep. 2019 Jan 24;9(1):439. doi: 10.1038/s41598-018-36881-4. Sci Rep. 2019. PMID: 30679635 Free PMC article.
Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding.
Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV. Vishnivetskiy SA, et al. Among authors: ostermaier mk. Cell Signal. 2013 Nov;25(11):2155-62. doi: 10.1016/j.cellsig.2013.07.009. Epub 2013 Jul 17. Cell Signal. 2013. PMID: 23872075 Free PMC article.
Functional map of arrestin-1 at single amino acid resolution.
Ostermaier MK, Peterhans C, Jaussi R, Deupi X, Standfuss J. Ostermaier MK, et al. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1825-30. doi: 10.1073/pnas.1319402111. Epub 2014 Jan 21. Proc Natl Acad Sci U S A. 2014. PMID: 24449856 Free PMC article.