Ostaszewski R - Search Results

1

Synthesis of novel, peptidic kinase inhibitors with cytostatic/cytotoxic activity.

Szymanski W, Zwolinska M, Klossowski S, Młynarczuk-Biały I, Biały L, Issat T, Malejczyk J, Ostaszewski R. Szymanski W, et al. Among authors: ostaszewski r. Bioorg Med Chem. 2014 Mar 1;22(5):1773-81. doi: 10.1016/j.bmc.2014.01.005. Epub 2014 Jan 10. Bioorg Med Chem. 2014. PMID: 24507826

2

The synthesis of a new type of anthracene DNA intercalator.

Ostaszewski R, Wilczyńska E, Wolszczak M. Ostaszewski R, et al. Bioorg Med Chem Lett. 1998 Nov 3;8(21):2995-6. doi: 10.1016/S0960-894X(98)00533-2. Bioorg Med Chem Lett. 1998. PMID: 9873662

3

Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach.

Mroczkiewicz M, Winkler K, Nowis D, Placha G, Golab J, Ostaszewski R. Mroczkiewicz M, et al. Among authors: ostaszewski r. J Med Chem. 2010 Feb 25;53(4):1509-18. doi: 10.1021/jm901619n. J Med Chem. 2010. PMID: 20112914

4

Studies toward novel peptidomimetic inhibitors of thioredoxin-thioredoxin reductase system.

Kłossowski S, Muchowicz A, Firczuk M, Swiech M, Redzej A, Golab J, Ostaszewski R. Kłossowski S, et al. Among authors: ostaszewski r. J Med Chem. 2012 Jan 12;55(1):55-67. doi: 10.1021/jm201359d. Epub 2011 Dec 20. J Med Chem. 2012. PMID: 22128876

5

Model studies on the first enzyme-catalyzed Ugi reaction.

Kłossowski S, Wiraszka B, Berłożecki S, Ostaszewski R. Kłossowski S, et al. Among authors: ostaszewski r. Org Lett. 2013 Feb 1;15(3):566-9. doi: 10.1021/ol3033829. Epub 2013 Jan 23. Org Lett. 2013. PMID: 23343100

6

Adenanthin targets proteins involved in the regulation of disulphide bonds.

Muchowicz A, Firczuk M, Chlebowska J, Nowis D, Stachura J, Barankiewicz J, Trzeciecka A, Kłossowski S, Ostaszewski R, Zagożdżon R, Pu JX, Sun HD, Golab J. Muchowicz A, et al. Among authors: ostaszewski r. Biochem Pharmacol. 2014 May 15;89(2):210-6. doi: 10.1016/j.bcp.2014.02.022. Epub 2014 Mar 11. Biochem Pharmacol. 2014. PMID: 24630929

7

SK053 triggers tumor cells apoptosis by oxidative stress-mediated endoplasmic reticulum stress.

Muchowicz A, Firczuk M, Wachowska M, Kujawa M, Jankowska-Steifer E, Gabrysiak M, Pilch Z, Kłossowski S, Ostaszewski R, Golab J. Muchowicz A, et al. Among authors: ostaszewski r. Biochem Pharmacol. 2015 Feb 15;93(4):418-27. doi: 10.1016/j.bcp.2014.12.019. Epub 2015 Jan 6. Biochem Pharmacol. 2015. PMID: 25573101

8

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma.

Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, Malinowska A, Czerwoniec A, Barankiewicz J, Domagala A, Chlebowska J, Prochorec-Sobieszek M, Winiarska M, Ostaszewski R, Gwizdalska I, Golab J, Nowis D, Firczuk M. Trzeciecka A, et al. Among authors: ostaszewski r. Oncotarget. 2016 Jan 12;7(2):1717-31. doi: 10.18632/oncotarget.6435. Oncotarget. 2016. PMID: 26636537 Free PMC article.

9

Enzymatic Ugi Reaction with Amines and Cyclic Imines.

Żądło-Dobrowolska A, Kłossowski S, Koszelewski D, Paprocki D, Ostaszewski R. Żądło-Dobrowolska A, et al. Among authors: ostaszewski r. Chemistry. 2016 Nov 7;22(46):16684-16689. doi: 10.1002/chem.201603412. Epub 2016 Sep 30. Chemistry. 2016. PMID: 27689846

10

Synthesis of (E)-α,β-unsaturated carboxylic esters derivatives from cyanoacetic acid via promiscuous enzyme-promoted cascade esterification/Knoevenagel reaction.

Wilk M, Trzepizur D, Koszelewski D, Brodzka A, Ostaszewski R. Wilk M, et al. Among authors: ostaszewski r. Bioorg Chem. 2019 Dec;93:102816. doi: 10.1016/j.bioorg.2019.02.041. Epub 2019 Feb 22. Bioorg Chem. 2019. PMID: 30799035

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