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22 results

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Page 1
An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams.
Mohammed KS, de Laurent ZR, Omuoyo DO, Lewa C, Gicheru E, Cheruiyot R, Bartilol B, Mutua S, Musyoki J, Gumba H, Mwacharo J, Riako D, Mwangi SJ, Gichuki BM, Nyamako L, Karani A, Karanja H, Mugo D, Gitonga JN, Njuguna S, Gumbi W, Tawa B, Tendwa M, Cheruiyot W, Sein Y, Nyambu JK, Patta SO, Thani TS, Maitha EK, Kitole B, Mwakinangu MS, Muslih BS, Otieno JO, Nyiro JU, Kiyuka P, Ndwiga L, Wamae K, Kimani D, Makale J, Morobe JM, Osoti V, Lambisia AW, Odundo C, Mwarumba S, Mutunga M, Bejon P, Tsofa B, Agoti CN, Ochola-Oyier LI. Mohammed KS, et al. Among authors: osoti v. Wellcome Open Res. 2022 Mar 4;5:162. doi: 10.12688/wellcomeopenres.16063.2. eCollection 2020. Wellcome Open Res. 2022. PMID: 35330938 Free PMC article.
No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.
Wamae K, Okanda D, Ndwiga L, Osoti V, Kimenyi KM, Abdi AI, Bejon P, Sutherland C, Ochola-Oyier LI. Wamae K, et al. Among authors: osoti v. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01067-19. doi: 10.1128/AAC.01067-19. Epub 2019 Oct 7. Antimicrob Agents Chemother. 2019. PMID: 31591113 Free PMC article.
Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast.
Agoti CN, Mutunga M, Lambisia AW, Kimani D, Cheruiyot R, Kiyuka P, Lewa C, Gicheru E, Tendwa M, Said Mohammed K, Osoti V, Makale J, Tawa B, Odundo C, Cheruiyot W, Nyamu W, Gumbi W, Mwacharo J, Nyamako L, Otieno E, Amadi D, Thoya J, Karani A, Mugo D, Musyoki J, Gumba H, Mwarumba S, M Gichuki B, Njuguna S, Riako D, Mutua S, Gitonga JN, Sein Y, Bartilol B, Mwangi SJ, O Omuoyo D, M Morobe J, de Laurent ZR, Bejon P, Ochola-Oyier LI, Tsofa B. Agoti CN, et al. Among authors: osoti v. Wellcome Open Res. 2021 Feb 3;5:186. doi: 10.12688/wellcomeopenres.16113.2. eCollection 2020. Wellcome Open Res. 2021. PMID: 33134555 Free PMC article.
A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.
Ndwiga L, Kimenyi KM, Wamae K, Osoti V, Akinyi M, Omedo I, Ishengoma DS, Duah-Quashie N, Andagalu B, Ghansah A, Amambua-Ngwa A, Tukwasibwe S, Tessema SK, Karema C, Djimde AA, Dondorp AM, Raman J, Snow RW, Bejon P, Ochola-Oyier LI. Ndwiga L, et al. Among authors: osoti v. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:155-161. doi: 10.1016/j.ijpddr.2021.06.001. Epub 2021 Jun 10. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34146993 Free PMC article. Review.
Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial.
Wamae K, Ndwiga L, Kharabora O, Kimenyi K, Osoti V, de Laurent Z, Wambua J, Musyoki J, Ngetsa C, Kalume P, Mwambingu G, Hamaluba M, van der Pluijm R, Dondorp AM, Bailey J, Juliano J, Bejon P, Ochola-Oyier L. Wamae K, et al. Among authors: osoti v. Wellcome Open Res. 2024 Mar 14;7:95. doi: 10.12688/wellcomeopenres.17736.2. eCollection 2022. Wellcome Open Res. 2024. PMID: 37456906 Free PMC article.
22 results