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Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders.
Zhao S, Lin Q, Xiong W, Li L, Straub L, Zhang D, Zapata R, Zhu Q, Sun XN, Zhang Z, Funcke JB, Li C, Chen S, Zhu Y, Jiang N, Li G, Xu Z, Wyler SC, Wang MY, Bai J, Han X, Kusminski CM, Zhang N, An Z, Elmquist JK, Osborn O, Liu C, Scherer PE. Zhao S, et al. Among authors: osborn o. Sci Transl Med. 2023 Nov 22;15(723):eade8460. doi: 10.1126/scitranslmed.ade8460. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992151
Adipocyte PU.1 knockout promotes insulin sensitivity in HFD-fed obese mice.
Lackey DE, Reis FCG, Isaac R, Zapata RC, El Ouarrat D, Lee YS, Bandyopadhyay G, Ofrecio JM, Oh DY, Osborn O. Lackey DE, et al. Among authors: osborn o. Sci Rep. 2019 Oct 14;9(1):14779. doi: 10.1038/s41598-019-51196-8. Sci Rep. 2019. PMID: 31611602 Free PMC article.
Dopamine D2 receptor signaling modulates pancreatic beta cell circadian rhythms.
Wei H, Zapata RC, Lopez-Valencia M, Aslanoglou D, Farino ZJ, Benner V, Osborn O, Freyberg Z, McCarthy MJ. Wei H, et al. Among authors: osborn o. Psychoneuroendocrinology. 2020 Mar;113:104551. doi: 10.1016/j.psyneuen.2019.104551. Epub 2019 Dec 23. Psychoneuroendocrinology. 2020. PMID: 31884319 Free PMC article.
Adipocytes control food intake and weight regain via Vacuolar-type H+ ATPase.
Zapata RC, Carretero M, Reis FCG, Chaudry BS, Ofrecio J, Zhang D, Sasik R, Ciaraldi T, Petrascheck M, Osborn O. Zapata RC, et al. Among authors: osborn o. Nat Commun. 2022 Aug 30;13(1):5092. doi: 10.1038/s41467-022-32764-5. Nat Commun. 2022. PMID: 36042358 Free PMC article.
Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia.
Zapata RC, Zhang D, Libster A, Porcu A, Montilla-Perez P, Nur A, Xu B, Zhang Z, Correa SM, Liu C, Telese F, Osborn O. Zapata RC, et al. Among authors: osborn o. Mol Psychiatry. 2023 May;28(5):1857-1867. doi: 10.1038/s41380-023-01981-9. Epub 2023 Feb 10. Mol Psychiatry. 2023. PMID: 36765131 Free PMC article. Review.
48 results