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c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice.
Bank U, Deiser K, Plaza-Sirvent C, Osbelt L, Witte A, Knop L, Labrenz R, Jänsch R, Richter F, Biswas A, Zenclussen AC, Vivier E, Romagnani C, Kühl AA, Dunay IR, Strowig T, Schmitz I, Schüler T. Bank U, et al. Among authors: osbelt l. Nat Commun. 2020 Feb 26;11(1):1056. doi: 10.1038/s41467-020-14782-3. Nat Commun. 2020. PMID: 32103006 Free PMC article.
Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production.
Osbelt L, Thiemann S, Smit N, Lesker TR, Schröter M, Gálvez EJC, Schmidt-Hohagen K, Pils MC, Mühlen S, Dersch P, Hiller K, Schlüter D, Neumann-Schaal M, Strowig T. Osbelt L, et al. PLoS Pathog. 2020 Mar 24;16(3):e1008448. doi: 10.1371/journal.ppat.1008448. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32208465 Free PMC article.
Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition.
Osbelt L, Wende M, Almási É, Derksen E, Muthukumarasamy U, Lesker TR, Galvez EJC, Pils MC, Schalk E, Chhatwal P, Färber J, Neumann-Schaal M, Fischer T, Schlüter D, Strowig T. Osbelt L, et al. Cell Host Microbe. 2021 Nov 10;29(11):1663-1679.e7. doi: 10.1016/j.chom.2021.09.003. Epub 2021 Oct 4. Cell Host Microbe. 2021. PMID: 34610293 Free article.
Laboratory mice with a wild microbiota generate strong allergic immune responses.
Ma J, Urgard E, Runge S, Classon CH, Mathä L, Stark JM, Cheng L, Álvarez JA, von Zedtwitz S, Baleviciute A, Martinez Hoyer S, Li M, Gernand AM, Osbelt L, Bielecka AA, Lesker TR, Huang HJ, Vrtala S, Boon L, Beyaert R, Adner M, Martinez Gonzalez I, Strowig T, Du J, Nylén S, Rosshart SP, Coquet JM. Ma J, et al. Among authors: osbelt l. Sci Immunol. 2023 Sep 29;8(87):eadf7702. doi: 10.1126/sciimmunol.adf7702. Epub 2023 Sep 29. Sci Immunol. 2023. PMID: 37774008
The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein.
Bussey KA, Lau U, Schumann S, Gallo A, Osbelt L, Stempel M, Arnold C, Wissing J, Gad HH, Hartmann R, Brune W, Jänsch L, Whitehouse A, Brinkmann MM. Bussey KA, et al. Among authors: osbelt l. PLoS Pathog. 2018 Mar 2;14(3):e1006937. doi: 10.1371/journal.ppat.1006937. eCollection 2018 Mar. PLoS Pathog. 2018. PMID: 29499066 Free PMC article.
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