Osawa T - Search Results

1

Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system.

Yamatsugu K, Katoh H, Yamashita T, Takahashi K, Aki S, Tatsumi T, Kaneko Y, Kawamura T, Miura M, Ishii M, Ohkubo K, Osawa T, Kodama T, Ishikawa S, Kanai M, Sugiyama A. Yamatsugu K, et al. Among authors: osawa t. Protein Expr Purif. 2022 Apr;192:106043. doi: 10.1016/j.pep.2021.106043. Epub 2021 Dec 30. Protein Expr Purif. 2022. PMID: 34973460 Free article.

2

Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.

Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, Shibuya M. Osawa T, et al. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20725-9. doi: 10.1073/pnas.1108462109. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143793 Free PMC article.

3

Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages.

Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, Shibuya M. Osawa T, et al. Cancer Res. 2013 May 15;73(10):3019-28. doi: 10.1158/0008-5472.CAN-12-3231. Epub 2013 Mar 14. Cancer Res. 2013. PMID: 23492365

4

The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases.

Minami T, Jiang S, Schadler K, Suehiro J, Osawa T, Oike Y, Miura M, Naito M, Kodama T, Ryeom S. Minami T, et al. Among authors: osawa t. Cell Rep. 2013 Aug 29;4(4):709-23. doi: 10.1016/j.celrep.2013.07.021. Epub 2013 Aug 15. Cell Rep. 2013. PMID: 23954784 Free PMC article.

5

Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.

Kondo A, Yamamoto S, Nakaki R, Shimamura T, Hamakubo T, Sakai J, Kodama T, Yoshida T, Aburatani H, Osawa T. Kondo A, et al. Among authors: osawa t. Cell Rep. 2017 Feb 28;18(9):2228-2242. doi: 10.1016/j.celrep.2017.02.006. Cell Rep. 2017. PMID: 28249167 Free article.

6

Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation.

Kondo A, Nonaka A, Shimamura T, Yamamoto S, Yoshida T, Kodama T, Aburatani H, Osawa T. Kondo A, et al. Among authors: osawa t. Mol Cell Biol. 2017 Aug 28;37(18):e00125-17. doi: 10.1128/MCB.00125-17. Print 2017 Sep 15. Mol Cell Biol. 2017. PMID: 28652266 Free PMC article.

7

Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα) Pemafibrate.

Sasaki Y, Raza-Iqbal S, Tanaka T, Murakami K, Anai M, Osawa T, Matsumura Y, Sakai J, Kodama T. Sasaki Y, et al. Among authors: osawa t. Int J Mol Sci. 2019 Nov 13;20(22):5682. doi: 10.3390/ijms20225682. Int J Mol Sci. 2019. PMID: 31766193 Free PMC article. Review.

8

Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content.

Sasaki Y, Asahiyama M, Tanaka T, Yamamoto S, Murakami K, Kamiya W, Matsumura Y, Osawa T, Anai M, Fruchart JC, Aburatani H, Sakai J, Kodama T. Sasaki Y, et al. Among authors: osawa t. Sci Rep. 2020 May 8;10(1):7818. doi: 10.1038/s41598-020-64902-8. Sci Rep. 2020. PMID: 32385406 Free PMC article.

9

Pathological complete remission of relapsed tumor by photo-activating antibody-mimetic drug conjugate treatment.

Kaneko Y, Yamatsugu K, Yamashita T, Takahashi K, Tanaka T, Aki S, Tatsumi T, Kawamura T, Miura M, Ishii M, Ohkubo K, Osawa T, Kodama T, Ishikawa S, Tsukagoshi M, Chansler M, Sugiyama A, Kanai M, Katoh H. Kaneko Y, et al. Among authors: osawa t. Cancer Sci. 2022 Dec;113(12):4350-4362. doi: 10.1111/cas.15565. Epub 2022 Sep 19. Cancer Sci. 2022. PMID: 36121618 Free PMC article.

10

Metabolic adaptations of cancer in extreme tumor microenvironments.

Nakahara R, Maeda K, Aki S, Osawa T. Nakahara R, et al. Among authors: osawa t. Cancer Sci. 2023 Apr;114(4):1200-1207. doi: 10.1111/cas.15722. Epub 2023 Jan 24. Cancer Sci. 2023. PMID: 36630222 Free PMC article. Review.

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