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The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma.
Carvalho A, Cunha C, Almeida AJ, Osório NS, Saraiva M, Teixeira-Coelho M, Pedreiro S, Torrado E, Domingues N, Gomes-Alves AG, Marques A, Lacerda JF, da Silva MG, Gomes M, Pinto AC, Torres F, Rendeiro P, Tavares P, Di Ianni M, Medeiros R, Heutink P, Bracci PM, Conde L, Ludovico P, Pedrosa J, Maciel P, Pitzurra L, Aversa F, Marques H, Paiva A, Skibola CF, Romani L, Castro AG, Rodrigues F. Carvalho A, et al. Among authors: osorio ns. Genes Immun. 2012 Feb;13(2):197-201. doi: 10.1038/gene.2011.59. Epub 2011 Aug 25. Genes Immun. 2012. PMID: 21866115 Free PMC article.
The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation.
Carvalho A, Osório NS, Saraiva M, Cunha C, Almeida AJ, Teixeira-Coelho M, Ludovico P, Pedrosa J, Pitzurra L, Aversa F, Romani L, Castro AG, Rodrigues F. Carvalho A, et al. Among authors: osorio ns. PLoS One. 2011;6(11):e28256. doi: 10.1371/journal.pone.0028256. Epub 2011 Nov 23. PLoS One. 2011. PMID: 22132241 Free PMC article.
A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.
Bastos HN, Osório NS, Castro AG, Ramos A, Carvalho T, Meira L, Araújo D, Almeida L, Boaventura R, Fragata P, Chaves C, Costa P, Portela M, Ferreira I, Magalhães SP, Rodrigues F, Sarmento-Castro R, Duarte R, Guimarães JT, Saraiva M. Bastos HN, et al. Among authors: osorio ns. PLoS One. 2016 Sep 16;11(9):e0162797. doi: 10.1371/journal.pone.0162797. eCollection 2016. PLoS One. 2016. PMID: 27636095 Free PMC article.
A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tuberculosis.
Bhatt K, Machado H, Osório NS, Sousa J, Cardoso F, Magalhães C, Chen B, Chen M, Kim J, Singh A, Ferreira CM, Castro AG, Torrado E, Jacobs WR Jr, Bhatt A, Saraiva M. Bhatt K, et al. Among authors: osorio ns. mSphere. 2018 Oct 31;3(5):e00352-18. doi: 10.1128/mSphere.00352-18. mSphere. 2018. PMID: 30381350 Free PMC article.
Predictors and outcomes of disseminated tuberculosis in an intermediate burden setting.
Meira L, Chaves C, Araújo D, Almeida L, Boaventura R, Ramos A, Carvalho T, Osório NS, Castro AG, Rodrigues F, Guimarães JT, Saraiva M, Bastos HN. Meira L, et al. Among authors: osorio ns. Pulmonology. 2019 Nov-Dec;25(6):320-327. doi: 10.1016/j.pulmoe.2018.11.001. Epub 2019 Feb 26. Pulmonology. 2019. PMID: 30819659 Free article.
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