Ortmann D - Search Results

1

Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools.

Zawada D, Kornherr J, Meier AB, Santamaria G, Dorn T, Nowak-Imialek M, Ortmann D, Zhang F, Lachmann M, Dreßen M, Ortiz M, Mascetti VL, Harmer SC, Nobles M, Tinker A, De Angelis MT, Pedersen RA, Grote P, Laugwitz KL, Moretti A, Goedel A. Zawada D, et al. Among authors: ortmann d. Nat Commun. 2023 Apr 3;14(1):1722. doi: 10.1038/s41467-023-36764-x. Nat Commun. 2023. PMID: 37012244 Free PMC article.

2

NANOG and CDX2 pattern distinct subtypes of human mesoderm during exit from pluripotency.

Mendjan S, Mascetti VL, Ortmann D, Ortiz M, Karjosukarso DW, Ng Y, Moreau T, Pedersen RA. Mendjan S, et al. Among authors: ortmann d. Cell Stem Cell. 2014 Sep 4;15(3):310-325. doi: 10.1016/j.stem.2014.06.006. Epub 2014 Jul 18. Cell Stem Cell. 2014. PMID: 25042702 Free article.

3

Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells.

Faial T, Bernardo AS, Mendjan S, Diamanti E, Ortmann D, Gentsch GE, Mascetti VL, Trotter MW, Smith JC, Pedersen RA. Faial T, et al. Among authors: ortmann d. Development. 2015 Jun 15;142(12):2121-35. doi: 10.1242/dev.117838. Epub 2015 May 26. Development. 2015. PMID: 26015544 Free PMC article.

4

Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes.

Pawlowski M, Ortmann D, Bertero A, Tavares JM, Pedersen RA, Vallier L, Kotter MRN. Pawlowski M, et al. Among authors: ortmann d. Stem Cell Reports. 2017 Apr 11;8(4):803-812. doi: 10.1016/j.stemcr.2017.02.016. Epub 2017 Mar 23. Stem Cell Reports. 2017. PMID: 28344001 Free PMC article.

5

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation.

Madrigal P, Deng S, Feng Y, Militi S, Goh KJ, Nibhani R, Grandy R, Osnato A, Ortmann D, Brown S, Pauklin S. Madrigal P, et al. Among authors: ortmann d. Nat Commun. 2023 Jan 25;14(1):405. doi: 10.1038/s41467-023-36116-9. Nat Commun. 2023. PMID: 36697417 Free PMC article.

6

BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.

Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger M, Smith JC, Bardwell L, Moffett A, Pedersen RA. Bernardo AS, et al. Among authors: ortmann d. Cell Stem Cell. 2011 Aug 5;9(2):144-55. doi: 10.1016/j.stem.2011.06.015. Cell Stem Cell. 2011. PMID: 21816365 Free PMC article.

7

A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels.

Xing Y, Zhao S, Wei Q, Gong S, Zhao X, Zhou F, Ai-Lamki R, Ortmann D, Du M, Pedersen R, Shang G, Si S, Morrell NW, Yang J. Xing Y, et al. Among authors: ortmann d. Eur Respir J. 2018 Apr 4;51(4):1702229. doi: 10.1183/13993003.02229-2017. Print 2018 Apr. Eur Respir J. 2018. PMID: 29449428 Free article.

8

The SMAD2/3 interactome reveals that TGFβ controls m⁶A mRNA methylation in pluripotency.

Bertero A, Brown S, Madrigal P, Osnato A, Ortmann D, Yiangou L, Kadiwala J, Hubner NC, de Los Mozos IR, Sadée C, Lenaerts AS, Nakanoh S, Grandy R, Farnell E, Ule J, Stunnenberg HG, Mendjan S, Vallier L. Bertero A, et al. Among authors: ortmann d. Nature. 2018 Mar 8;555(7695):256-259. doi: 10.1038/nature25784. Epub 2018 Feb 28. Nature. 2018. PMID: 29489750 Free PMC article.

9

Human axial progenitors generate trunk neural crest cells in vitro.

Frith TJ, Granata I, Wind M, Stout E, Thompson O, Neumann K, Stavish D, Heath PR, Ortmann D, Hackland JO, Anastassiadis K, Gouti M, Briscoe J, Wilson V, Johnson SL, Placzek M, Guarracino MR, Andrews PW, Tsakiridis A. Frith TJ, et al. Among authors: ortmann d. Elife. 2018 Aug 10;7:e35786. doi: 10.7554/eLife.35786. Elife. 2018. PMID: 30095409 Free PMC article.

10

Generation of functional hepatocytes by forward programming with nuclear receptors.

Tomaz RA, Zacharis ED, Bachinger F, Wurmser A, Yamamoto D, Petrus-Reurer S, Morell CM, Dziedzicka D, Wesley BT, Geti I, Segeritz CP, de Brito MC, Chhatriwala M, Ortmann D, Saeb-Parsy K, Vallier L. Tomaz RA, et al. Among authors: ortmann d. Elife. 2022 Aug 12;11:e71591. doi: 10.7554/eLife.71591. Elife. 2022. PMID: 35959725 Free PMC article.

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