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Advances in the clinical management of high-risk Wilms tumors.
Ortiz MV, Koenig C, Armstrong AE, Brok J, de Camargo B, Mavinkurve-Groothuis AMC, Herrera TBV, Venkatramani R, Woods AD, Dome JS, Spreafico F. Ortiz MV, et al. Pediatr Blood Cancer. 2023 May;70 Suppl 2(Suppl 2):e30342. doi: 10.1002/pbc.30342. Pediatr Blood Cancer. 2023. PMID: 37096797 Free PMC article. Review.
Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Ortiz MV, Ahmed S, Burns M, Henssen AG, Hollmann TJ, MacArthur I, Gunasekera S, Gaewsky L, Bradwin G, Ryan J, Letai A, He Y, Naranjo A, Chi YY, LaQuaglia M, Heaton T, Cifani P, Dome JS, Gadd S, Perlman E, Mullen E, Steen H, Kentsis A. Ortiz MV, et al. JCI Insight. 2019 Aug 8;4(15):e127098. doi: 10.1172/jci.insight.127098. eCollection 2019 Aug 8. JCI Insight. 2019. PMID: 31391345 Free PMC article.
11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood.
Fiala EM, Ortiz MV, Kennedy JA, Glodzik D, Fleischut MH, Duffy KA, Hathaway ER, Heaton T, Gerstle JT, Steinherz P, Shukla N, McNeer N, Tkachuk K, Bouvier N, Cadoo K, Carlo MI, Latham A, Dubard Gault M, Joseph V, Kemel Y, Kentsis A, Stadler Z, La Quaglia M, Papaemmanuil E, Friedman D, Ganguly A, Kung A, Offit K, Kalish JM, Walsh MF. Fiala EM, et al. Among authors: ortiz mv. Cancer. 2020 Jul 1;126(13):3114-3121. doi: 10.1002/cncr.32907. Epub 2020 Apr 22. Cancer. 2020. PMID: 32320050 Free PMC article.
Bromodomain 4 inhibition leads to MYCN downregulation in Wilms tumor.
Woods AD, Berlow NE, Ortiz MV, Dela Cruz F, Siddiquee A, Coutinho DF, Purohit R, Freier KET, Michalek JE, Lathara M, Matlock K, Srivivasa G, Royer-Pokora B, Veselska R, Kung AL, Keller C. Woods AD, et al. Among authors: ortiz mv. Pediatr Blood Cancer. 2022 Feb;69(2):e29401. doi: 10.1002/pbc.29401. Epub 2021 Oct 24. Pediatr Blood Cancer. 2022. PMID: 34693628 Free PMC article.
Advances in the clinical management of high-risk Wilms tumors.
Ortiz MV, Koenig C, Armstrong AE, Brok J, de Camargo B, Mavinkurve-Groothuis AMC, Herrera TBV, Venkatramani R, Woods AD, Dome JS, Spreafico F. Ortiz MV, et al. Pediatr Blood Cancer. 2023 Mar;70(3):e30153. doi: 10.1002/pbc.30153. Epub 2023 Jan 10. Pediatr Blood Cancer. 2023. PMID: 36625399 Review.
Hallmark discoveries in the biology of Wilms tumour.
Perotti D, Williams RD, Wegert J, Brzezinski J, Maschietto M, Ciceri S, Gisselsson D, Gadd S, Walz AL, Furtwaengler R, Drost J, Al-Saadi R, Evageliou N, Gooskens SL, Hong AL, Murphy AJ, Ortiz MV, O'Sullivan MJ, Mullen EA, van den Heuvel-Eibrink MM, Fernandez CV, Graf N, Grundy PE, Geller JI, Dome JS, Perlman EJ, Gessler M, Huff V, Pritchard-Jones K. Perotti D, et al. Among authors: ortiz mv. Nat Rev Urol. 2024 Mar;21(3):158-180. doi: 10.1038/s41585-023-00824-0. Epub 2023 Oct 17. Nat Rev Urol. 2024. PMID: 37848532 Review.
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