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Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism.
Martínez-Torres S, Bergadà-Martínez A, Ortega JE, Galera-López L, Hervera A, de Los Reyes-Ramírez L, Ortega-Álvaro A, Remmers F, Muñoz-Moreno E, Soria G, Del Río JA, Lutz B, Ruíz-Ortega JÁ, Meana JJ, Maldonado R, Ozaita A. Martínez-Torres S, et al. Among authors: ortega alvaro a. Neuropsychopharmacology. 2023 Jan;48(2):341-350. doi: 10.1038/s41386-022-01436-9. Epub 2022 Sep 10. Neuropsychopharmacology. 2023. PMID: 36088492 Free PMC article.
Peripheral and central CB1 cannabinoid receptors control stress-induced impairment of memory consolidation.
Busquets-Garcia A, Gomis-González M, Srivastava RK, Cutando L, Ortega-Alvaro A, Ruehle S, Remmers F, Bindila L, Bellocchio L, Marsicano G, Lutz B, Maldonado R, Ozaita A. Busquets-Garcia A, et al. Among authors: ortega alvaro a. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9904-9. doi: 10.1073/pnas.1525066113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528659 Free PMC article.
Decreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid CB₂ receptors.
Aracil-Fernández A, Trigo JM, García-Gutiérrez MS, Ortega-Álvaro A, Ternianov A, Navarro D, Robledo P, Berbel P, Maldonado R, Manzanares J. Aracil-Fernández A, et al. Among authors: ortega alvaro a. Neuropsychopharmacology. 2012 Jun;37(7):1749-63. doi: 10.1038/npp.2012.22. Epub 2012 Mar 14. Neuropsychopharmacology. 2012. PMID: 22414816 Free PMC article.
Orally Active Peptide Vector Allows Using Cannabis to Fight Pain While Avoiding Side Effects.
Gallo M, Moreno E, Defaus S, Ortega-Alvaro A, Gonzalez A, Robledo P, Cavaco M, Neves V, Castanho MARB, Casadó V, Pardo L, Maldonado R, Andreu D. Gallo M, et al. Among authors: ortega alvaro a. J Med Chem. 2021 May 27;64(10):6937-6948. doi: 10.1021/acs.jmedchem.1c00484. Epub 2021 Apr 22. J Med Chem. 2021. PMID: 33887904 Free PMC article.
Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine.
Ternianov A, Pérez-Ortiz JM, Solesio ME, García-Gutiérrez MS, Ortega-Álvaro A, Navarrete F, Leiva C, Galindo MF, Manzanares J. Ternianov A, et al. Neurobiol Aging. 2012 Feb;33(2):421.e1-16. doi: 10.1016/j.neurobiolaging.2010.09.012. Epub 2010 Oct 27. Neurobiol Aging. 2012. PMID: 20980074
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