Orsale M - Search Results

1

Structure of calmodulin complexed with an olfactory CNG channel fragment and role of the central linker: residual dipolar couplings to evaluate calmodulin binding modes outside the kinase family.

Contessa GM, Orsale M, Melino S, Torre V, Paci M, Desideri A, Cicero DO. Contessa GM, et al. Among authors: orsale m. J Biomol NMR. 2005 Mar;31(3):185-99. doi: 10.1007/s10858-005-0165-1. J Biomol NMR. 2005. PMID: 15803393

2

Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy.

Orsale M, Melino S, Contessa GM, Torre V, Andreotti G, Motta A, Paci M, Desideri A, Cicero DO. Orsale M, et al. FEBS Lett. 2003 Jul 31;548(1-3):11-6. doi: 10.1016/s0014-5793(03)00716-6. FEBS Lett. 2003. PMID: 12885399 Free article.

3

Azotobacter vinelandii rhodanese: selenium loading and ion interaction studies.

Melino S, Cicero DO, Orsale M, Forlani F, Pagani S, Paci M. Melino S, et al. Among authors: orsale m. Eur J Biochem. 2003 Oct;270(20):4208-15. doi: 10.1046/j.1432-1033.2003.03818.x. Eur J Biochem. 2003. PMID: 14519133 Free article.

4

Structural rearrangements of the two domains of Azotobacter vinelandii rhodanese upon sulfane sulfur release: essential molecular dynamics, 15N NMR relaxation and deuterium exchange on the uniformly labeled protein.

Cicero DO, Melino S, Orsale M, Brancato G, Amadei A, Forlani F, Pagani S, Paci M. Cicero DO, et al. Among authors: orsale m. Int J Biol Macromol. 2003 Dec;33(4-5):193-201. doi: 10.1016/j.ijbiomac.2003.08.010. Int J Biol Macromol. 2003. PMID: 14607364

5

A novel method using nuclear magnetic resonance for plasma protein binding assessment in drug discovery programs.

Gallo M, Matteucci S, Alaimo N, Pitti E, Orsale MV, Summa V, Cicero DO, Monteagudo E. Gallo M, et al. Among authors: orsale mv. J Pharm Biomed Anal. 2019 Apr 15;167:21-29. doi: 10.1016/j.jpba.2019.01.049. Epub 2019 Jan 31. J Pharm Biomed Anal. 2019. PMID: 30738240 Free article.

6

Surface changes and role of buried water molecules during the sulfane sulfur transfer in rhodanese from Azotobacter vinelandii: a fluorescence quenching and nuclear magnetic relaxation dispersion spectroscopic study.

Fasano M, Orsale M, Melino S, Nicolai E, Forlani F, Rosato N, Cicero D, Pagani S, Paci M. Fasano M, et al. Among authors: orsale m. Biochemistry. 2003 Jul 22;42(28):8550-7. doi: 10.1021/bi0273359. Biochemistry. 2003. PMID: 12859202

7

A single-run liquid chromatography mass spectrometry method to quantify neuroactive kynurenine pathway metabolites in rat plasma.

Orsatti L, Speziale R, Orsale MV, Caretti F, Veneziano M, Zini M, Monteagudo E, Lyons K, Beconi M, Chan K, Herbst T, Toledo-Sherman L, Munoz-Sanjuan I, Bonelli F, Dominguez C. Orsatti L, et al. Among authors: orsale mv. J Pharm Biomed Anal. 2015 Mar 25;107:426-31. doi: 10.1016/j.jpba.2015.01.030. Epub 2015 Jan 24. J Pharm Biomed Anal. 2015. PMID: 25668794

8

High-throughput microsomal stability assay for screening new chemical entities in drug discovery.

Fonsi M, Orsale MV, Monteagudo E. Fonsi M, et al. Among authors: orsale mv. J Biomol Screen. 2008 Oct;13(9):862-9. doi: 10.1177/1087057108323911. Epub 2008 Sep 23. J Biomol Screen. 2008. PMID: 18812573

9

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

Ontoria JM, Paonessa G, Ponzi S, Ferrigno F, Nizi E, Biancofiore I, Malancona S, Graziani R, Roberts D, Willis P, Bresciani A, Gennari N, Cecchetti O, Monteagudo E, Orsale MV, Veneziano M, Di Marco A, Cellucci A, Laufer R, Altamura S, Summa V, Harper S. Ontoria JM, et al. Among authors: orsale mv. ACS Med Chem Lett. 2016 Mar 5;7(5):454-9. doi: 10.1021/acsmedchemlett.5b00468. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190592 Free PMC article.

10

The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease.

Monteagudo E, Fonsi M, Chu X, Bleasby K, Evers R, Pucci V, Orsale MV, Cianetti S, Ferrara M, Harper S, Laufer R, Rowley M, Summa V. Monteagudo E, et al. Among authors: orsale mv. Xenobiotica. 2010 Dec;40(12):826-39. doi: 10.3109/00498254.2010.519061. Epub 2010 Oct 7. Xenobiotica. 2010. PMID: 20925584

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