Orozco M - Search Results

1

Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α.

Pous J, Baginski B, Martin-Malpartida P, González L, Scarpa M, Aragon E, Ruiz L, Mees RA, Iglesias-Fernández J, Orozco M, Nebreda AR, Macias MJ. Pous J, et al. Among authors: orozco m. Nat Commun. 2023 Dec 1;14(1):7920. doi: 10.1038/s41467-023-43763-5. Nat Commun. 2023. PMID: 38040726 Free PMC article.

2

Correlated motions are a fundamental property of β-sheets.

Fenwick RB, Orellana L, Esteban-Martín S, Orozco M, Salvatella X. Fenwick RB, et al. Among authors: orozco m. Nat Commun. 2014 Jun 11;5:4070. doi: 10.1038/ncomms5070. Nat Commun. 2014. PMID: 24915882 Free article.

3

Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.

Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR, Aloy P. Jaeger S, et al. Among authors: orozco m. Cancer Res. 2017 Jan 15;77(2):459-469. doi: 10.1158/0008-5472.CAN-16-0097. Epub 2016 Nov 22. Cancer Res. 2017. PMID: 27879272

4

Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations.

Kuzmanic A, Sutto L, Saladino G, Nebreda AR, Gervasio FL, Orozco M. Kuzmanic A, et al. Among authors: orozco m. Elife. 2017 Apr 26;6:e22175. doi: 10.7554/eLife.22175. Elife. 2017. PMID: 28445123 Free PMC article.

5

Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.

González L, Díaz L, Pous J, Baginski B, Duran-Corbera A, Scarpa M, Brun-Heath I, Igea A, Martin-Malpartida P, Ruiz L, Pallara C, Esguerra M, Colizzi F, Mayor-Ruiz C, Biondi RM, Soliva R, Macias MJ, Orozco M, Nebreda AR. González L, et al. Among authors: orozco m. Nat Commun. 2023 Jun 12;14(1):3318. doi: 10.1038/s41467-023-39051-x. Nat Commun. 2023. PMID: 37308482 Free PMC article.

6

Theoretical calculations, synthesis and base pairing properties of oligonucleotides containing 8-amino-2'-deoxyadenosine.

García RG, Ferrer E, Macías MJ, Eritja R, Orozco M. García RG, et al. Among authors: orozco m. Nucleic Acids Res. 1999 May 1;27(9):1991-8. doi: 10.1093/nar/27.9.1991. Nucleic Acids Res. 1999. PMID: 10198432 Free PMC article.

7

Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations.

Orellana L, Yoluk O, Carrillo O, Orozco M, Lindahl E. Orellana L, et al. Among authors: orozco m. Nat Commun. 2016 Aug 31;7:12575. doi: 10.1038/ncomms12575. Nat Commun. 2016. PMID: 27578633 Free PMC article.

8

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.

Garcia-Lopez A, Tessaro F, Jonker HRA, Wacker A, Richter C, Comte A, Berntenis N, Schmucki R, Hatje K, Petermann O, Chiriano G, Perozzo R, Sciarra D, Konieczny P, Faustino I, Fournet G, Orozco M, Artero R, Metzger F, Ebeling M, Goekjian P, Joseph B, Schwalbe H, Scapozza L. Garcia-Lopez A, et al. Among authors: orozco m. Nat Commun. 2018 May 23;9(1):2032. doi: 10.1038/s41467-018-04110-1. Nat Commun. 2018. PMID: 29795225 Free PMC article.

9

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor.

Escobedo A, Topal B, Kunze MBA, Aranda J, Chiesa G, Mungianu D, Bernardo-Seisdedos G, Eftekharzadeh B, Gairí M, Pierattelli R, Felli IC, Diercks T, Millet O, García J, Orozco M, Crehuet R, Lindorff-Larsen K, Salvatella X. Escobedo A, et al. Among authors: orozco m. Nat Commun. 2019 May 2;10(1):2034. doi: 10.1038/s41467-019-09923-2. Nat Commun. 2019. PMID: 31048691 Free PMC article.

10

Exploring the Conformational Landscape of Bioactive Small Molecules.

Zivanovic S, Colizzi F, Moreno D, Hospital A, Soliva R, Orozco M. Zivanovic S, et al. Among authors: orozco m. J Chem Theory Comput. 2020 Oct 13;16(10):6575-6585. doi: 10.1021/acs.jctc.0c00304. Epub 2020 Sep 2. J Chem Theory Comput. 2020. PMID: 32786895

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

535 results

Search Page