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Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB.
Holliday H, Roden D, Junankar S, Wu SZ, Baker LA, Krisp C, Chan CL, McFarland A, Skhinas JN, Cox TR, Pal B, Huntington ND, Ormandy CJ, Carroll JS, Visvader J, Molloy MP, Swarbrick A. Holliday H, et al. Among authors: ormandy cj. iScience. 2021 Jan 20;24(2):102072. doi: 10.1016/j.isci.2021.102072. eCollection 2021 Feb 19. iScience. 2021. PMID: 33554073 Free PMC article.
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer.
Baker LA, Holliday H, Roden D, Krisp C, Wu SZ, Junankar S, Serandour AA, Mohammed H, Nair R, Sankaranarayanan G, Law AMK, McFarland A, Simpson PT, Lakhani S, Dodson E, Selinger C, Anderson L, Samimi G, Hacker NF, Lim E, Ormandy CJ, Naylor MJ, Simpson K, Nikolic I, O'Toole S, Kaplan W, Cowley MJ, Carroll JS, Molloy M, Swarbrick A. Baker LA, et al. Among authors: ormandy cj. Breast Cancer Res. 2020 Jun 11;22(1):63. doi: 10.1186/s13058-020-01306-6. Breast Cancer Res. 2020. PMID: 32527287 Free PMC article.
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype.
Junankar S, Baker LA, Roden DL, Nair R, Elsworth B, Gallego-Ortega D, Lacaze P, Cazet A, Nikolic I, Teo WS, Yang J, McFarland A, Harvey K, Naylor MJ, Lakhani SR, Simpson PT, Raghavendra A, Saunus J, Madore J, Kaplan W, Ormandy C, Millar EK, O'Toole S, Yun K, Swarbrick A. Junankar S, et al. Nat Commun. 2015 Mar 27;6:6548. doi: 10.1038/ncomms7548. Nat Commun. 2015. PMID: 25813983 Free article.
Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer.
Owens TW, Rogers RL, Best S, Ledger A, Mooney AM, Ferguson A, Shore P, Swarbrick A, Ormandy CJ, Simpson PT, Carroll JS, Visvader J, Naylor MJ. Owens TW, et al. Among authors: ormandy cj. Cancer Res. 2014 Sep 15;74(18):5277-5286. doi: 10.1158/0008-5472.CAN-14-0053. Epub 2014 Jul 23. Cancer Res. 2014. PMID: 25056120 Free PMC article.
ELF5 modulates the estrogen receptor cistrome in breast cancer.
Piggin CL, Roden DL, Law AMK, Molloy MP, Krisp C, Swarbrick A, Naylor MJ, Kalyuga M, Kaplan W, Oakes SR, Gallego-Ortega D, Clark SJ, Carroll JS, Bartonicek N, Ormandy CJ. Piggin CL, et al. Among authors: ormandy cj. PLoS Genet. 2020 Jan 2;16(1):e1008531. doi: 10.1371/journal.pgen.1008531. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31895944 Free PMC article.
Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1.
Teo WS, Holliday H, Karthikeyan N, Cazet AS, Roden DL, Harvey K, Konrad CV, Murali R, Varghese BA, Thankamony AP, Chan CL, McFarland A, Junankar S, Ye S, Yang J, Nikolic I, Shah JS, Baker LA, Millar EKA, Naylor MJ, Ormandy CJ, Lakhani SR, Kaplan W, Mellick AS, O'Toole SA, Swarbrick A, Nair R. Teo WS, et al. Among authors: ormandy cj. Front Cell Dev Biol. 2020 Jul 17;8:552. doi: 10.3389/fcell.2020.00552. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32766238 Free PMC article.
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.
Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, Caldon CE, Stone A, Allerdice SL, Valdes-Mora F, Launchbury R, Statham AL, Armstrong N, Alles MC, Young A, Egger A, Au W, Piggin CL, Evans CJ, Ledger A, Brummer T, Oakes SR, Kaplan W, Gee JM, Nicholson RI, Sutherland RL, Swarbrick A, Naylor MJ, Clark SJ, Carroll JS, Ormandy CJ. Kalyuga M, et al. Among authors: ormandy cj. PLoS Biol. 2012;10(12):e1001461. doi: 10.1371/journal.pbio.1001461. Epub 2012 Dec 27. PLoS Biol. 2012. PMID: 23300383 Free PMC article.
c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer.
Nair R, Roden DL, Teo WS, McFarland A, Junankar S, Ye S, Nguyen A, Yang J, Nikolic I, Hui M, Morey A, Shah J, Pfefferle AD, Usary J, Selinger C, Baker LA, Armstrong N, Cowley MJ, Naylor MJ, Ormandy CJ, Lakhani SR, Herschkowitz JI, Perou CM, Kaplan W, O'Toole SA, Swarbrick A. Nair R, et al. Among authors: ormandy cj. Oncogene. 2014 Jul 24;33(30):3992-4002. doi: 10.1038/onc.2013.368. Epub 2013 Sep 23. Oncogene. 2014. PMID: 24056965
ALTEN: A High-Fidelity Primary Tissue-Engineering Platform to Assess Cellular Responses Ex Vivo.
Law AMK, Chen J, Colino-Sanguino Y, Fuente LR, Fang G, Grimes SM, Lu H, Huang RJ, Boyle ST, Venhuizen J, Castillo L, Tavakoli J, Skhinas JN, Millar EKA, Beretov J, Rossello FJ, Tipper JL, Ormandy CJ, Samuel MS, Cox TR, Martelotto L, Jin D, Valdes-Mora F, Ji HP, Gallego-Ortega D. Law AMK, et al. Among authors: ormandy cj. Adv Sci (Weinh). 2022 Jul;9(21):e2103332. doi: 10.1002/advs.202103332. Epub 2022 May 25. Adv Sci (Weinh). 2022. PMID: 35611998 Free PMC article.
119 results