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ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.
Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, Caldon CE, Stone A, Allerdice SL, Valdes-Mora F, Launchbury R, Statham AL, Armstrong N, Alles MC, Young A, Egger A, Au W, Piggin CL, Evans CJ, Ledger A, Brummer T, Oakes SR, Kaplan W, Gee JM, Nicholson RI, Sutherland RL, Swarbrick A, Naylor MJ, Clark SJ, Carroll JS, Ormandy CJ. Kalyuga M, et al. Among authors: ormandy cj. PLoS Biol. 2012;10(12):e1001461. doi: 10.1371/journal.pbio.1001461. Epub 2012 Dec 27. PLoS Biol. 2012. PMID: 23300383 Free PMC article.
The mammary cellular hierarchy and breast cancer.
Oakes SR, Gallego-Ortega D, Ormandy CJ. Oakes SR, et al. Among authors: ormandy cj. Cell Mol Life Sci. 2014 Nov;71(22):4301-24. doi: 10.1007/s00018-014-1674-4. Epub 2014 Jul 31. Cell Mol Life Sci. 2014. PMID: 25080108 Free PMC article. Review.
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ. Gallego-Ortega D, et al. Among authors: ormandy cj. PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec. PLoS Biol. 2015. PMID: 26717410 Free PMC article.
Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.
Erami Z, Herrmann D, Warren SC, Nobis M, McGhee EJ, Lucas MC, Leung W, Reischmann N, Mrowinska A, Schwarz JP, Kadir S, Conway JRW, Vennin C, Karim SA, Campbell AD, Gallego-Ortega D, Magenau A, Murphy KJ, Ridgway RA, Law AM, Walters SN, Grey ST, Croucher DR, Zhang L, Herzog H, Hardeman EC, Gunning PW, Ormandy CJ, Evans TRJ, Strathdee D, Sansom OJ, Morton JP, Anderson KI, Timpson P. Erami Z, et al. Among authors: ormandy cj. Cell Rep. 2016 Jan 5;14(1):152-167. doi: 10.1016/j.celrep.2015.12.020. Epub 2015 Dec 24. Cell Rep. 2016. PMID: 26725115 Free PMC article.
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib.
Young AI, Law AM, Castillo L, Chong S, Cullen HD, Koehler M, Herzog S, Brummer T, Lee EF, Fairlie WD, Lucas MC, Herrmann D, Allam A, Timpson P, Watkins DN, Millar EK, O'Toole SA, Gallego-Ortega D, Ormandy CJ, Oakes SR. Young AI, et al. Among authors: ormandy cj. Breast Cancer Res. 2016 Dec 8;18(1):125. doi: 10.1186/s13058-016-0781-6. Breast Cancer Res. 2016. PMID: 27931239 Free PMC article.
ELF5 modulates the estrogen receptor cistrome in breast cancer.
Piggin CL, Roden DL, Law AMK, Molloy MP, Krisp C, Swarbrick A, Naylor MJ, Kalyuga M, Kaplan W, Oakes SR, Gallego-Ortega D, Clark SJ, Carroll JS, Bartonicek N, Ormandy CJ. Piggin CL, et al. Among authors: ormandy cj. PLoS Genet. 2020 Jan 2;16(1):e1008531. doi: 10.1371/journal.pgen.1008531. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31895944 Free PMC article.
119 results