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Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance.
Thompson PD, MacDougall DE, Newton RS, Margulies JR, Hanselman JC, Orloff DG, McKenney JM, Ballantyne CM. Thompson PD, et al. Among authors: orloff dg. J Clin Lipidol. 2016 May-Jun;10(3):556-67. doi: 10.1016/j.jacl.2015.12.025. Epub 2016 Jan 6. J Clin Lipidol. 2016. PMID: 27206943 Free article. Clinical Trial.
A highly bioavailable omega-3 free fatty acid formulation improves the cardiovascular risk profile in high-risk, statin-treated patients with residual hypertriglyceridemia (the ESPRIT trial).
Maki KC, Orloff DG, Nicholls SJ, Dunbar RL, Roth EM, Curcio D, Johnson J, Kling D, Davidson MH. Maki KC, et al. Among authors: orloff dg. Clin Ther. 2013 Sep;35(9):1400-11.e1-3. doi: 10.1016/j.clinthera.2013.07.420. Epub 2013 Aug 30. Clin Ther. 2013. PMID: 23998969 Clinical Trial.
Effects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial.
Dunbar RL, Nicholls SJ, Maki KC, Roth EM, Orloff DG, Curcio D, Johnson J, Kling D, Davidson MH. Dunbar RL, et al. Among authors: orloff dg. Lipids Health Dis. 2015 Sep 2;14:98. doi: 10.1186/s12944-015-0100-8. Lipids Health Dis. 2015. PMID: 26328624 Free PMC article. Clinical Trial.
Anti-lipid trial endpoints.
Orloff DG. Orloff DG. Am J Ther. 1999 Mar;6(2):115-9. doi: 10.1097/00045391-199903000-00009. Am J Ther. 1999. PMID: 10610245 Review. No abstract available.
28 results