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FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
Wang XX, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg AZ, Levi J, Kopp JB, Field A, Hill A, Lucia S, Qiu L, Jiang T, Peng Y, Orlicky D, Garcia G, Herman-Edelstein M, D'Agati V, Henriksen K, Adorini L, Pruzanski M, Xie C, Krausz KW, Gonzalez FJ, Ranjit S, Dvornikov A, Gratton E, Levi M. Wang XX, et al. Among authors: orlicky d, d agati v. J Am Soc Nephrol. 2018 Jan;29(1):118-137. doi: 10.1681/ASN.2017020222. Epub 2017 Oct 31. J Am Soc Nephrol. 2018. PMID: 29089371 Free PMC article.
Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy.
Lanaspa MA, Ishimoto T, Cicerchi C, Tamura Y, Roncal-Jimenez CA, Chen W, Tanabe K, Andres-Hernando A, Orlicky DJ, Finol E, Inaba S, Li N, Rivard CJ, Kosugi T, Sanchez-Lozada LG, Petrash JM, Sautin YY, Ejaz AA, Kitagawa W, Garcia GE, Bonthron DT, Asipu A, Diggle CP, Rodriguez-Iturbe B, Nakagawa T, Johnson RJ. Lanaspa MA, et al. J Am Soc Nephrol. 2014 Nov;25(11):2526-38. doi: 10.1681/ASN.2013080901. Epub 2014 May 29. J Am Soc Nephrol. 2014. PMID: 24876114 Free PMC article.
Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice.
Friedman JE, Dobrinskikh E, Alfonso-Garcia A, Fast A, Janssen RC, Soderborg TK, Anderson AL, Reisz JA, D'Alessandro A, Frank DN, Robertson CE, de la Houssaye BA, Johnson LK, Orlicky DJ, Wang XX, Levi M, Potma EO, El Kasmi KC, Jonscher KR. Friedman JE, et al. Among authors: d alessandro a, orlicky dj. Hepatol Commun. 2018 Jan 22;2(3):313-328. doi: 10.1002/hep4.1139. eCollection 2018 Mar. Hepatol Commun. 2018. PMID: 29507905 Free PMC article.
Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice.
Takahashi S, Luo Y, Ranjit S, Xie C, Libby AE, Orlicky DJ, Dvornikov A, Wang XX, Myakala K, Jones BA, Bhasin K, Wang D, McManaman JL, Krausz KW, Gratton E, Ir D, Robertson CE, Frank DN, Gonzalez FJ, Levi M. Takahashi S, et al. Among authors: orlicky dj. J Biol Chem. 2020 Apr 3;295(14):4733-4747. doi: 10.1074/jbc.RA119.011913. Epub 2020 Feb 19. J Biol Chem. 2020. PMID: 32075905 Free PMC article.
The developing murine lung is susceptible to acetaminophen toxicity.
Dobrinskikh E, Sherlock LG, Orlicky DJ, Zheng L, De Dios R, Balasubramaniyan D, Sizemore T, Butler B, Wright CJ. Dobrinskikh E, et al. Among authors: orlicky dj. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L969-L978. doi: 10.1152/ajplung.00072.2021. Epub 2021 Mar 24. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33759579 Free PMC article.
Pulmonary implications of acetaminophen exposures independent of hepatic toxicity.
Dobrinskikh E, Al-Juboori SI, Zarate MA, Zheng L, De Dios R, Balasubramaniyan D, Sherlock LG, Orlicky DJ, Wright CJ. Dobrinskikh E, et al. Among authors: orlicky dj. Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L941-L953. doi: 10.1152/ajplung.00234.2021. Epub 2021 Sep 29. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34585971 Free PMC article.
215 results