Orkin SH - Search Results

1

MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.

Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang YY, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, Barabási AL, Loscalzo J, Chan SY. Parikh VN, et al. Among authors: orkin sh. Circulation. 2012 Mar 27;125(12):1520-32. doi: 10.1161/CIRCULATIONAHA.111.060269. Epub 2012 Feb 27. Circulation. 2012. PMID: 22371328 Free PMC article.

2

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.

McDevitt MA, Shivdasani RA, Fujiwara Y, Yang H, Orkin SH. McDevitt MA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6781-5. doi: 10.1073/pnas.94.13.6781. Proc Natl Acad Sci U S A. 1997. PMID: 9192642 Free PMC article.

3

An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice.

McDevitt MA, Fujiwara Y, Shivdasani RA, Orkin SH. McDevitt MA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7976-81. doi: 10.1073/pnas.94.15.7976. Proc Natl Acad Sci U S A. 1997. PMID: 9223298 Free PMC article.

4

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.

Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. Shivdasani RA, et al. Among authors: orkin sh. EMBO J. 1997 Jul 1;16(13):3965-73. doi: 10.1093/emboj/16.13.3965. EMBO J. 1997. PMID: 9233806 Free PMC article.

5

Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL.

Wang LC, Kuo F, Fujiwara Y, Gilliland DG, Golub TR, Orkin SH. Wang LC, et al. Among authors: orkin sh. EMBO J. 1997 Jul 16;16(14):4374-83. doi: 10.1093/emboj/16.14.4374. EMBO J. 1997. PMID: 9250681 Free PMC article.

6

The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation.

Visvader JE, Mao X, Fujiwara Y, Hahm K, Orkin SH. Visvader JE, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13707-12. doi: 10.1073/pnas.94.25.13707. Proc Natl Acad Sci U S A. 1997. PMID: 9391090 Free PMC article.

7

Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development.

Visvader JE, Fujiwara Y, Orkin SH. Visvader JE, et al. Among authors: orkin sh. Genes Dev. 1998 Feb 15;12(4):473-9. doi: 10.1101/gad.12.4.473. Genes Dev. 1998. PMID: 9472016 Free PMC article.

8

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice.

Mao X, Fujiwara Y, Orkin SH. Mao X, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5037-42. doi: 10.1073/pnas.96.9.5037. Proc Natl Acad Sci U S A. 1999. PMID: 10220414 Free PMC article.

9

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain.

Mao X, Fujiwara Y, Chapdelaine A, Yang H, Orkin SH. Mao X, et al. Among authors: orkin sh. Blood. 2001 Jan 1;97(1):324-6. doi: 10.1182/blood.v97.1.324. Blood. 2001. PMID: 11133778 Free article.

10

GATA1-Cre mediates Piga gene inactivation in the erythroid/megakaryocytic lineage and leads to circulating red cells with a partial deficiency in glycosyl phosphatidylinositol-linked proteins (paroxysmal nocturnal hemoglobinuria type II cells).

Jasinski M, Keller P, Fujiwara Y, Orkin SH, Bessler M. Jasinski M, et al. Among authors: orkin sh. Blood. 2001 Oct 1;98(7):2248-55. doi: 10.1182/blood.v98.7.2248. Blood. 2001. PMID: 11568013 Free article.

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