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343 results

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Safety and efficacy of doravirine as first-line therapy in adults with HIV-1: week 192 results from the open-label extensions of the DRIVE-FORWARD and DRIVE-AHEAD phase 3 trials.
Orkin C, Molina JM, Cahn P, Lombaard J, Supparatpinyo K, Kumar S, Campbell H, Wan H, Teal V, Jin Xu Z, Asante-Appiah E, Sklar P, Teppler H, Lahoulou R; DRIVE-FORWARD and DRIVE-AHEAD collaborators. Orkin C, et al. Lancet HIV. 2024 Feb;11(2):e75-e85. doi: 10.1016/S2352-3018(23)00258-8. Epub 2023 Dec 20. Lancet HIV. 2024. PMID: 38141637 Clinical Trial.
Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT).
Paton NI, Stöhr W, Arenas-Pinto A, Clarke A, Williams I, Johnson M, Orkin C, Chen F, Lee V, Winston A, Gompels M, Fox J, Sanders K, Dunn DT; Protease Inhibitor monotherapy Versus Ongoing Triple therapy (PIVOT) Trial Team. Paton NI, et al. Among authors: orkin c. EClinicalMedicine. 2024 Feb 10;69:102457. doi: 10.1016/j.eclinm.2024.102457. eCollection 2024 Mar. EClinicalMedicine. 2024. PMID: 38361989 Free PMC article.
The associations between age and the development of laboratory abnormalities and treatment discontinuation for reasons other than virological failure in the first year of highly active antiretroviral therapy.
Sabin CA, Smith CJ, Delpech V, Anderson J, Bansi L, Gilson R, Schwenk A, Leen C, Gazzard B, Porter K, Mackie N, Fisher M, Orkin C, Johnson M, Easterbrook P, Hill T, Phillips AN; UK Collaborative HIV Cohort (CHIC) Study. Sabin CA, et al. Among authors: orkin c. HIV Med. 2009 Jan;10(1):35-43. doi: 10.1111/j.1468-1293.2008.00654.x. Epub 2008 Nov 10. HIV Med. 2009. PMID: 19018876 Free article.
Immediate Versus Deferred Switching From a Boosted Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen in Virologically Suppressed Patients With High Cardiovascular Risk or Age ≥50 Years: Final 96-Week Results of the NEAT022 Study.
Gatell JM, Assoumou L, Moyle G, Waters L, Johnson M, Domingo P, Fox J, Martinez E, Stellbrink HJ, Guaraldi G, Masia M, Gompels M, De Wit S, Florence E, Esser S, Raffi F, Stephan C, Rockstroh J, Giacomelli A, Vera J, Bernardino JI, Winston A, Saumoy M, Gras J, Katlama C, Pozniak AL; European Network for AIDS Treatment 022 (NEAT022) Study Group. Gatell JM, et al. Clin Infect Dis. 2019 Feb 1;68(4):597-606. doi: 10.1093/cid/ciy505. Clin Infect Dis. 2019. PMID: 29912307 Clinical Trial.
Ageism: the -ism affecting the lives of older people living with HIV.
Guaraldi G, Milic J, Cascio M, Mussini C, Martinez E, Levin J, Calzavara D, Mbewe R, Falutz J, Orkin C, Cesari M, Lazarus JV. Guaraldi G, et al. Among authors: orkin c. Lancet HIV. 2024 Jan;11(1):e52-e59. doi: 10.1016/S2352-3018(23)00226-6. Epub 2023 Nov 28. Lancet HIV. 2024. PMID: 38040011 Review.
Changing face of mpox.
Cevik M, Orkin C. Cevik M, et al. Among authors: orkin c. Clin Microbiol Infect. 2023 Dec;29(12):1485-1486. doi: 10.1016/j.cmi.2023.10.011. Epub 2023 Oct 14. Clin Microbiol Infect. 2023. PMID: 37844695 No abstract available.
Mpox: The Reemergence of an Old Disease and Inequities.
Thornhill JP, Gandhi M, Orkin C. Thornhill JP, et al. Among authors: orkin c. Annu Rev Med. 2024 Jan 29;75:159-175. doi: 10.1146/annurev-med-080122-030714. Epub 2023 Oct 3. Annu Rev Med. 2024. PMID: 37788486 Free article. Review.
A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study.
Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N, Kapil V, Godec T, Apea V, Flint J, Orkin C, Rathod KS, Ahluwalia A. Shabbir A, et al. Among authors: orkin c. Trials. 2023 Sep 16;24(1):593. doi: 10.1186/s13063-023-07616-2. Trials. 2023. PMID: 37715222 Free PMC article.
343 results