Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

17 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors.
Keeley AB, Kopranovic A, Di Lorenzo V, Ábrányi-Balogh P, Jänsch N, Lai LN, Petri L, Orgován Z, Pölöske D, Orlova A, Németh AG, Desczyk C, Imre T, Bajusz D, Moriggl R, Meyer-Almes FJ, Keserü GM. Keeley AB, et al. Among authors: orgovan z. J Med Chem. 2024 Jan 11;67(1):572-585. doi: 10.1021/acs.jmedchem.3c01779. Epub 2023 Dec 19. J Med Chem. 2024. PMID: 38113354 Free PMC article.
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency.
Orgován Z, Péczka N, Petri L, Ábrányi-Balogh P, Ranđelović I, Tóth S, Szakács G, Nyíri K, Vértessy B, Pálfy G, Vida I, Perczel A, Tóvári J, Keserű GM. Orgován Z, et al. Eur J Med Chem. 2023 Mar 15;250:115212. doi: 10.1016/j.ejmech.2023.115212. Epub 2023 Feb 15. Eur J Med Chem. 2023. PMID: 36842271 Free article.
Electrophilic warheads in covalent drug discovery: an overview.
Péczka N, Orgován Z, Ábrányi-Balogh P, Keserű GM. Péczka N, et al. Among authors: orgovan z. Expert Opin Drug Discov. 2022 Apr;17(4):413-422. doi: 10.1080/17460441.2022.2034783. Epub 2022 Feb 6. Expert Opin Drug Discov. 2022. PMID: 35129005 Review.
Structural impact of GTP binding on downstream KRAS signaling.
Menyhárd DK, Pálfy G, Orgován Z, Vida I, Keserű GM, Perczel A. Menyhárd DK, et al. Among authors: orgovan z. Chem Sci. 2020 Aug 19;11(34):9272-9289. doi: 10.1039/d0sc03441j. Chem Sci. 2020. PMID: 34094198 Free PMC article.
[Allele-specific inhibitors of mutant KRAS are in the focus of RASopathy consortium].
Nyíri K, Koppány G, Pálfy G, Vida I, Tóth S, Orgován Z, Ranđelović I, Baranyi M, Molnár E, Keserû MG, Tóvári J, Perczel A, Vértessy BG, Tímár J. Nyíri K, et al. Among authors: orgovan z. Magy Onkol. 2019 Dec 9;63(4):310-323. Epub 2019 Nov 25. Magy Onkol. 2019. PMID: 31821386 Free article. Hungarian.
17 results