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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Rosser EC, Piper CJM, Matei DE, Blair PA, Rendeiro AF, Orford M, Alber DG, Krausgruber T, Catalan D, Klein N, Manson JJ, Drozdov I, Bock C, Wedderburn LR, Eaton S, Mauri C. Rosser EC, et al. Among authors: orford m. Cell Metab. 2020 Apr 7;31(4):837-851.e10. doi: 10.1016/j.cmet.2020.03.003. Epub 2020 Mar 25. Cell Metab. 2020. PMID: 32213346 Free PMC article.
Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells.
Bilip M, Shah S, Mathiyalakan M, Tagalakis AD, Hart SL, Maeshima R, Eaton S, Orford M, Irving E, Di Florio A, Simons C, Stoker AW. Bilip M, et al. Among authors: orford m. J Drug Target. 2020 Jul;28(6):643-654. doi: 10.1080/1061186X.2019.1710157. Epub 2020 Jan 14. J Drug Target. 2020. PMID: 31903789 Free PMC article.
Role of CD14+ monocyte-derived oxidised mitochondrial DNA in the inflammatory interferon type 1 signature in juvenile dermatomyositis.
Wilkinson MGL, Moulding D, McDonnell TCR, Orford M, Wincup C, Ting JYJ, Otto GW, Restuadi R, Kelberman D, Papadopoulou C, Castellano S, Eaton S, Deakin CT, Rosser EC, Wedderburn LR. Wilkinson MGL, et al. Among authors: orford m. Ann Rheum Dis. 2023 May;82(5):658-669. doi: 10.1136/ard-2022-223469. Epub 2022 Dec 23. Ann Rheum Dis. 2023. PMID: 36564154 Free PMC article.
Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure.
Meran L, Massie I, Campinoti S, Weston AE, Gaifulina R, Tullie L, Faull P, Orford M, Kucharska A, Baulies A, Novellasdemunt L, Angelis N, Hirst E, König J, Tedeschi AM, Pellegata AF, Eli S, Snijders AP, Collinson L, Thapar N, Thomas GMH, Eaton S, Bonfanti P, De Coppi P, Li VSW. Meran L, et al. Among authors: orford m. Nat Med. 2020 Oct;26(10):1593-1601. doi: 10.1038/s41591-020-1024-z. Epub 2020 Sep 7. Nat Med. 2020. PMID: 32895569 Free PMC article.
Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders.
Soria LR, Gurung S, De Sabbata G, Perocheau DP, De Angelis A, Bruno G, Polishchuk E, Paris D, Cuomo P, Motta A, Orford M, Khalil Y, Eaton S, Mills PB, Waddington SN, Settembre C, Muro AF, Baruteau J, Brunetti-Pierri N. Soria LR, et al. Among authors: orford m. EMBO Mol Med. 2021 Feb 5;13(2):e13158. doi: 10.15252/emmm.202013158. Epub 2020 Dec 28. EMBO Mol Med. 2021. PMID: 33369168 Free PMC article.
43 results