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Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance.
Botta C, Perez C, Larrayoz M, Puig N, Cedena MT, Termini R, Goicoechea I, Rodriguez S, Zabaleta A, Lopez A, Sarvide S, Blanco L, Papetti DM, Nobile MS, Besozzi D, Gentile M, Correale P, Siragusa S, Oriol A, González-Garcia ME, Sureda A, de Arriba F, Rios Tamayo R, Moraleda JM, Gironella M, Hernandez MT, Bargay J, Palomera L, Pérez-Montaña A, Goldschmidt H, Avet-Loiseau H, Roccaro A, Orfao A, Martinez-Lopez J, Rosiñol L, Lahuerta JJ, Blade J, Mateos MV, San-Miguel JF, Martinez Climent JA, Paiva B; Programa Para el Estudio de la Terapéutica en Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) cooperative group; iMMunocell study group. Botta C, et al. Among authors: orfao a. Nat Commun. 2023 Sep 20;14(1):5825. doi: 10.1038/s41467-023-41562-6. Nat Commun. 2023. PMID: 37730678 Free PMC article.
Immunophenotypic evaluation of the plasma cell compartment in multiple myeloma: a tool for comparing the efficacy of different treatment strategies and predicting outcome.
San Miguel JF, Almeida J, Mateo G, Bladé J, López-Berges C, Caballero D, Hernández J, Moro MJ, Fernández-Calvo J, Díaz-Mediavilla J, Palomera L, Orfao A. San Miguel JF, et al. Among authors: orfao a. Blood. 2002 Mar 1;99(5):1853-6. doi: 10.1182/blood.v99.5.1853. Blood. 2002. PMID: 11861305 Free article.
Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival.
Mateos MV, García-Sanz R, López-Pérez R, Moro MJ, Ocio E, Hernández J, Megido M, Caballero MD, Fernández-Calvo J, Bárez A, Almeida J, Orfão A, González M, San Miguel JF. Mateos MV, et al. Among authors: orfao a. Br J Haematol. 2002 Sep;118(4):1034-40. doi: 10.1046/j.1365-2141.2002.03749.x. Br J Haematol. 2002. PMID: 12199782 Free article.
Immunophenotypic analysis of myelodysplastic syndromes.
Del Cañizo MC, Fernández ME, López A, Vidriales B, Villarón E, Arroyo JL, Ortuño F, Orfao A, San Miguel JF. Del Cañizo MC, et al. Among authors: orfao a. Haematologica. 2003 Apr;88(4):402-7. Haematologica. 2003. PMID: 12681967
Minimal residual disease monitoring by flow cytometry.
Vidriales MB, San-Miguel JF, Orfao A, Coustan-Smith E, Campana D. Vidriales MB, et al. Among authors: orfao a. Best Pract Res Clin Haematol. 2003 Dec;16(4):599-612. doi: 10.1016/s1521-6926(03)00067-7. Best Pract Res Clin Haematol. 2003. PMID: 14592645
829 results