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Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation.
Panfili E, Mondanelli G, Orabona C, Belladonna ML, Gargaro M, Fallarino F, Orecchini E, Prontera P, Proietti E, Frontino G, Tirelli E, Iacono A, Vacca C, Puccetti P, Grohmann U, Esposito S, Pallotta MT. Panfili E, et al. Among authors: orecchini e. Hum Mol Genet. 2021 Apr 26;30(3-4):265-276. doi: 10.1093/hmg/ddab040. Hum Mol Genet. 2021. PMID: 33693650 Free PMC article.
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma.
Orecchini E, Belladonna ML, Pallotta MT, Volpi C, Zizi L, Panfili E, Gargaro M, Fallarino F, Rossini S, Suvieri C, Macchiarulo A, Bicciato S, Mondanelli G, Orabona C. Orecchini E, et al. Oncoimmunology. 2023 Jan 26;12(1):2170095. doi: 10.1080/2162402X.2023.2170095. eCollection 2023. Oncoimmunology. 2023. PMID: 36733497 Free PMC article.
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity.
Serafini M, Torre E, Aprile S, Grosso ED, Gesù A, Griglio A, Colombo G, Travelli C, Paiella S, Adamo A, Orecchini E, Coletti A, Pallotta MT, Ugel S, Massarotti A, Pirali T, Fallarini S. Serafini M, et al. Among authors: orecchini e. J Med Chem. 2020 Mar 26;63(6):3047-3065. doi: 10.1021/acs.jmedchem.9b01809. Epub 2020 Mar 17. J Med Chem. 2020. PMID: 32150677
29 results