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Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars.
Luukkonen PK, Sädevirta S, Zhou Y, Kayser B, Ali A, Ahonen L, Lallukka S, Pelloux V, Gaggini M, Jian C, Hakkarainen A, Lundbom N, Gylling H, Salonen A, Orešič M, Hyötyläinen T, Orho-Melander M, Rissanen A, Gastaldelli A, Clément K, Hodson L, Yki-Järvinen H. Luukkonen PK, et al. Among authors: oresic m. Diabetes Care. 2018 Aug;41(8):1732-1739. doi: 10.2337/dc18-0071. Epub 2018 May 29. Diabetes Care. 2018. PMID: 29844096 Free PMC article. Clinical Trial.
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.
Kolak M, Westerbacka J, Velagapudi VR, Wågsäter D, Yetukuri L, Makkonen J, Rissanen A, Häkkinen AM, Lindell M, Bergholm R, Hamsten A, Eriksson P, Fisher RM, Oresic M, Yki-Järvinen H. Kolak M, et al. Among authors: oresic m. Diabetes. 2007 Aug;56(8):1960-8. doi: 10.2337/db07-0111. Epub 2007 Jul 9. Diabetes. 2007. PMID: 17620421
ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan.
Hiukka A, Ståhlman M, Pettersson C, Levin M, Adiels M, Teneberg S, Leinonen ES, Hultén LM, Wiklund O, Oresic M, Olofsson SO, Taskinen MR, Ekroos K, Borén J. Hiukka A, et al. Among authors: oresic m. Diabetes. 2009 Sep;58(9):2018-26. doi: 10.2337/db09-0206. Epub 2009 Jun 5. Diabetes. 2009. PMID: 19502413 Free PMC article.
362 results