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Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus.
Belardinelli JM, Verma D, Li W, Avanzi C, Wiersma CJ, Williams JT, Johnson BK, Zimmerman M, Whittel N, Angala B, Wang H, Jones V, Dartois V, de Moura VCN, Gonzalez-Juarrero M, Pearce C, Schenkel AR, Malcolm KC, Nick JA, Charman SA, Wells TNC, Podell BK, Vennerstrom JL, Ordway DJ, Abramovitch RB, Jackson M. Belardinelli JM, et al. Among authors: ordway dj. Sci Transl Med. 2022 Feb 23;14(633):eabj3860. doi: 10.1126/scitranslmed.abj3860. Epub 2022 Feb 23. Sci Transl Med. 2022. PMID: 35196022 Free PMC article.
XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-gamma by CD4 T cells and participates in granuloma stability.
Ordway D, Higgins DM, Sanchez-Campillo J, Spencer JS, Henao-Tamayo M, Harton M, Orme IM, Gonzalez Juarrero M. Ordway D, et al. J Leukoc Biol. 2007 Nov;82(5):1221-9. doi: 10.1189/jlb.0607426. Epub 2007 Aug 15. J Leukoc Biol. 2007. PMID: 17699612
Animal model of Mycobacterium abscessus lung infection.
Ordway D, Henao-Tamayo M, Smith E, Shanley C, Harton M, Troudt J, Bai X, Basaraba RJ, Orme IM, Chan ED. Ordway D, et al. J Leukoc Biol. 2008 Jun;83(6):1502-11. doi: 10.1189/jlb.1007696. Epub 2008 Feb 29. J Leukoc Biol. 2008. PMID: 18310351
101 results