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Dystrophin is a tumor suppressor in human cancers with myogenic programs.
Wang Y, Marino-Enriquez A, Bennett RR, Zhu M, Shen Y, Eilers G, Lee JC, Henze J, Fletcher BS, Gu Z, Fox EA, Antonescu CR, Fletcher CD, Guo X, Raut CP, Demetri GD, van de Rijn M, Ordog T, Kunkel LM, Fletcher JA. Wang Y, et al. Among authors: ordog t. Nat Genet. 2014 Jun;46(6):601-6. doi: 10.1038/ng.2974. Epub 2014 May 4. Nat Genet. 2014. PMID: 24793134 Free PMC article.
Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract.
Gomez-Pinilla PJ, Gibbons SJ, Bardsley MR, Lorincz A, Pozo MJ, Pasricha PJ, Van de Rijn M, West RB, Sarr MG, Kendrick ML, Cima RR, Dozois EJ, Larson DW, Ordog T, Farrugia G. Gomez-Pinilla PJ, et al. Among authors: ordog t. Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1370-81. doi: 10.1152/ajpgi.00074.2009. Epub 2009 Apr 16. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19372102 Free PMC article.
Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.
Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, Ordog T. Hayashi Y, et al. Among authors: ordog t. PLoS One. 2013 Oct 7;8(10):e76822. doi: 10.1371/journal.pone.0076822. eCollection 2013. PLoS One. 2013. PMID: 24116170 Free PMC article.
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.
Hayashi Y, Bardsley MR, Toyomasu Y, Milosavljevic S, Gajdos GB, Choi KM, Reid-Lombardo KM, Kendrick ML, Bingener-Casey J, Tang CM, Sicklick JK, Gibbons SJ, Farrugia G, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Ramachandran A, Ordog T. Hayashi Y, et al. Among authors: ordog t. Gastroenterology. 2015 Aug;149(2):420-32.e16. doi: 10.1053/j.gastro.2015.04.006. Epub 2015 Apr 9. Gastroenterology. 2015. PMID: 25865047 Free PMC article.
Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs).
Heinrich MC, Patterson J, Beadling C, Wang Y, Debiec-Rychter M, Dewaele B, Corless CL, Duensing A, Raut CP, Rubin B, Ordog T, van de Rijn M, Call J, Mühlenberg T, Fletcher JA, Bauer S. Heinrich MC, et al. Among authors: ordog t. Clin Sarcoma Res. 2019 Mar 5;9:3. doi: 10.1186/s13569-019-0112-7. eCollection 2019. Clin Sarcoma Res. 2019. PMID: 30867899 Free PMC article.
Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors.
Bardsley MR, Horváth VJ, Asuzu DT, Lorincz A, Redelman D, Hayashi Y, Popko LN, Young DL, Lomberk GA, Urrutia RA, Farrugia G, Rubin BP, Ordog T. Bardsley MR, et al. Among authors: ordog t. Gastroenterology. 2010 Sep;139(3):942-52. doi: 10.1053/j.gastro.2010.05.083. Epub 2010 Jun 4. Gastroenterology. 2010. PMID: 20621681 Free PMC article.
Ano1 as a regulator of proliferation.
Stanich JE, Gibbons SJ, Eisenman ST, Bardsley MR, Rock JR, Harfe BD, Ordog T, Farrugia G. Stanich JE, et al. Among authors: ordog t. Am J Physiol Gastrointest Liver Physiol. 2011 Dec;301(6):G1044-51. doi: 10.1152/ajpgi.00196.2011. Epub 2011 Sep 22. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21940901 Free PMC article.
FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.
Schwamb B, Pick R, Fernández SB, Völp K, Heering J, Dötsch V, Bösser S, Jung J, Beinoraviciute-Kellner R, Wesely J, Zörnig I, Hammerschmidt M, Nowak M, Penzel R, Zatloukal K, Joos S, Rieker RJ, Agaimy A, Söder S, Reid-Lombardo KM, Kendrick ML, Bardsley MR, Hayashi Y, Asuzu DT, Syed SA, Ordog T, Zörnig M. Schwamb B, et al. Among authors: ordog t. Int J Cancer. 2015 Sep 15;137(6):1318-29. doi: 10.1002/ijc.29498. Epub 2015 Mar 12. Int J Cancer. 2015. PMID: 25716227 Free PMC article.
Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.
Tang CM, Lee TE, Syed SA, Burgoyne AM, Leonard SY, Gao F, Chan JC, Shi E, Chmielecki J, Morosini D, Wang K, Ross JS, Kendrick ML, Bardsley MR, Siena M, Mao J, Harismendy O, Ordog T, Sicklick JK. Tang CM, et al. Among authors: ordog t. Oncotarget. 2016 Nov 29;7(48):78226-78241. doi: 10.18632/oncotarget.12909. Oncotarget. 2016. PMID: 27793025 Free PMC article.
Changes in interstitial cells of cajal with age in the human stomach and colon.
Gomez-Pinilla PJ, Gibbons SJ, Sarr MG, Kendrick ML, Shen KR, Cima RR, Dozois EJ, Larson DW, Ordog T, Pozo MJ, Farrugia G. Gomez-Pinilla PJ, et al. Among authors: ordog t. Neurogastroenterol Motil. 2011 Jan;23(1):36-44. doi: 10.1111/j.1365-2982.2010.01590.x. Epub 2010 Aug 19. Neurogastroenterol Motil. 2011. PMID: 20723073 Free PMC article.
125 results