Oprea TI - Search Results

1

Activation of Rho Family GTPases by Small Molecules.

Palsuledesai CC, Surviladze Z, Waller A, Miscioscia TF, Guo Y, Wu Y, Strouse J, Romero E, Salas VM, Curpan R, Young S, Carter M, Foutz T, Galochkina Z, Ames H, Haynes MK, Edwards BS, Nicolotti O, Luo L, Ursu O, Bologa CG, Oprea TI, Wandinger-Ness A, Sklar LA. Palsuledesai CC, et al. Among authors: oprea ti. ACS Chem Biol. 2018 Jun 15;13(6):1514-1524. doi: 10.1021/acschembio.8b00038. Epub 2018 May 24. ACS Chem Biol. 2018. PMID: 29746086 Free PMC article.

2

MTD-PLS: A PLS-based variant of the MTD method. 2. Mapping ligand-receptor interactions. Enzymatic acetic acid esters hydrolysis.

Kurunczi L, Olah M, Oprea TI, Bologa C, Simon Z. Kurunczi L, et al. Among authors: oprea ti. J Chem Inf Comput Sci. 2002 Jul-Aug;42(4):841-6. doi: 10.1021/ci010124a. J Chem Inf Comput Sci. 2002. PMID: 12132884

3

Flow cytometry for high-throughput, high-content screening.

Edwards BS, Oprea T, Prossnitz ER, Sklar LA. Edwards BS, et al. Curr Opin Chem Biol. 2004 Aug;8(4):392-8. doi: 10.1016/j.cbpa.2004.06.007. Curr Opin Chem Biol. 2004. PMID: 15288249 Review.

4

An automated PLS search for biologically relevant QSAR descriptors.

Olah M, Bologa C, Oprea TI. Olah M, et al. Among authors: oprea ti. J Comput Aided Mol Des. 2004 Jul-Sep;18(7-9):437-49. doi: 10.1007/s10822-004-4060-8. J Comput Aided Mol Des. 2004. PMID: 15729845

5

Dissociation of I domain and global conformational changes in LFA-1: refinement of small molecule-I domain structure-activity relationships.

Larson RS, Davis T, Bologa C, Semenuk G, Vijayan S, Li Y, Oprea T, Chigaev A, Buranda T, Wagner CR, Sklar LA. Larson RS, et al. Biochemistry. 2005 Mar 22;44(11):4322-31. doi: 10.1021/bi048187k. Biochemistry. 2005. PMID: 15766261

6

High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands.

Young SM, Bologa C, Prossnitz ER, Oprea TI, Sklar LA, Edwards BS. Young SM, et al. Among authors: oprea ti. J Biomol Screen. 2005 Jun;10(4):374-82. doi: 10.1177/1087057105274532. J Biomol Screen. 2005. PMID: 15964939

7

Post-high-throughput screening analysis: an empirical compound prioritization scheme.

Oprea TI, Bologa CG, Edwards BS, Prossnitz ER, Sklar LA. Oprea TI, et al. J Biomol Screen. 2005 Aug;10(5):419-26. doi: 10.1177/1087057104272660. J Biomol Screen. 2005. PMID: 16093551

8

Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists.

Edwards BS, Bologa C, Young SM, Balakin KV, Prossnitz ER, Savchuck NP, Sklar LA, Oprea TI. Edwards BS, et al. Among authors: oprea ti. Mol Pharmacol. 2005 Nov;68(5):1301-10. doi: 10.1124/mol.105.014068. Epub 2005 Aug 23. Mol Pharmacol. 2005. PMID: 16118363

9

Descriptor collision and confusion: toward the design of descriptors to mask chemical structures.

Bologa C, Allu TK, Olah M, Kappler MA, Oprea TI. Bologa C, et al. Among authors: oprea ti. J Comput Aided Mol Des. 2005 Sep-Oct;19(9-10):625-35. doi: 10.1007/s10822-005-9020-4. Epub 2005 Dec 2. J Comput Aided Mol Des. 2005. PMID: 16322910

10

Strategies for compound selection.

Olah MM, Bologa CG, Oprea TI. Olah MM, et al. Among authors: oprea ti. Curr Drug Discov Technol. 2004 Oct;1(3):211-20. doi: 10.2174/1570163043334965. Curr Drug Discov Technol. 2004. PMID: 16472248 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

230 results

Search Page