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AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms.
Morande PE, Yan XJ, Sepulveda J, Seija N, Marquez ME, Sotelo N, Abreu C, Crispo M, Fernández-Graña G, Rego N, Bois T, Methot SP, Palacios F, Remedi V, Rai KR, Buschiazzo A, Di Noia JM, Navarrete MA, Chiorazzi N, Oppezzo P. Morande PE, et al. Among authors: oppezzo p. Blood. 2021 Jul 22;138(3):246-258. doi: 10.1182/blood.2020008654. Blood. 2021. PMID: 34292322 Free article.
High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease.
Palacios F, Moreno P, Morande P, Abreu C, Correa A, Porro V, Landoni AI, Gabus R, Giordano M, Dighiero G, Pritsch O, Oppezzo P. Palacios F, et al. Among authors: oppezzo p. Blood. 2010 Jun 3;115(22):4488-96. doi: 10.1182/blood-2009-12-257758. Epub 2010 Mar 16. Blood. 2010. PMID: 20233972 Free article.
[No title available]
[No authors listed] [No authors listed] PMID: 33651893
Dissecting chronic lymphocytic leukemia microenvironment signals in patients with unmutated disease: microRNA-22 regulates phosphatase and tensin homolog/AKT/FOXO1 pathway in proliferative leukemic cells.
Palacios F, Prieto D, Abreu C, Ruiz S, Morande P, Fernández-Calero T, Libisch G, Landoni AI, Oppezzo P. Palacios F, et al. Among authors: oppezzo p. Leuk Lymphoma. 2015 May;56(5):1560-5. doi: 10.3109/10428194.2014.990900. Epub 2015 Jan 29. Leuk Lymphoma. 2015. PMID: 25430416
HSP90 inhibitors decrease AID levels and activity in mice and in human cells.
Montamat-Sicotte D, Litzler LC, Abreu C, Safavi S, Zahn A, Orthwein A, Müschen M, Oppezzo P, Muñoz DP, Di Noia JM. Montamat-Sicotte D, et al. Among authors: oppezzo p. Eur J Immunol. 2015 Aug;45(8):2365-76. doi: 10.1002/eji.201545462. Epub 2015 May 18. Eur J Immunol. 2015. PMID: 25912253 Free PMC article.
LPL protein in Chronic Lymphocytic Leukaemia have different origins in Mutated and Unmutated patients. Advances for a new prognostic marker in CLL.
Prieto D, Seija N, Uriepero A, Souto-Padron T, Oliver C, Irigoin V, Guillermo C, Navarrete MA, Inés Landoni A, Dighiero G, Gabus R, Giordano M, Oppezzo P. Prieto D, et al. Among authors: oppezzo p. Br J Haematol. 2018 Aug;182(4):521-525. doi: 10.1111/bjh.15427. Epub 2018 Jun 28. Br J Haematol. 2018. PMID: 29953583 Free article.
60 results