Oppermann U - Search Results

1

The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms.

Chang CH, Liu F, Militi S, Hester S, Nibhani R, Deng S, Dunford J, Rendek A, Soonawalla Z, Fischer R, Oppermann U, Pauklin S. Chang CH, et al. Among authors: oppermann u. Nat Commun. 2024 Apr 27;15(1):3580. doi: 10.1038/s41467-024-47680-z. Nat Commun. 2024. PMID: 38678032 Free PMC article.

2

Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.

Xiong Y, Greschik H, Johansson C, Seifert L, Gamble V, Park KS, Fagan V, Li F, Chau I, Vedadi M, Arrowsmith CH, Brennan P, Fedorov O, Jung M, Farnie G, Liu J, Oppermann U, Schüle R, Jin J. Xiong Y, et al. Among authors: oppermann u. J Med Chem. 2024 Apr 11;67(7):5837-5853. doi: 10.1021/acs.jmedchem.4c00121. Epub 2024 Mar 27. J Med Chem. 2024. PMID: 38533580

3

Correcting PCR amplification errors in unique molecular identifiers to generate accurate numbers of sequencing molecules.

Sun J, Philpott M, Loi D, Li S, Monteagudo-Mesas P, Hoffman G, Robson J, Mehta N, Gamble V, Brown T Jr, Brown T Sr, Canzar S, Oppermann U, Cribbs AP. Sun J, et al. Among authors: oppermann u. Nat Methods. 2024 Mar;21(3):401-405. doi: 10.1038/s41592-024-02168-y. Epub 2024 Feb 5. Nat Methods. 2024. PMID: 38317008 Free PMC article.

4

Longitudinal dynamics and clinically available predictors of poor response to COVID-19 vaccination in multiple myeloma.

Agarwal G, Moore S, Sadler R, Varghese S, Turner A, Chen LY, Larham J, Gray N, Carty O, Barrett J, Koshiaris C, Kothari J, Bowcock S, Oppermann U, Gamble V, Cook G, Kyriakou C, Drayson M, Basu S, McDonald S, McKinley S, Gooding S, Javaid MK, Ramasamy K. Agarwal G, et al. Among authors: oppermann u. Haematologica. 2024 Jan 25. doi: 10.3324/haematol.2023.284286. Online ahead of print. Haematologica. 2024. PMID: 38268439 Free article.

5

PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo.

Brown EJ, Balaguer-Lluna L, Cribbs AP, Philpott M, Campo L, Browne M, Wong JF, Oppermann U, Carcaboso ÁM, Bullock AN, Farnie G. Brown EJ, et al. Among authors: oppermann u. Sci Rep. 2024 Jan 3;14(1):328. doi: 10.1038/s41598-023-48652-x. Sci Rep. 2024. PMID: 38172189 Free PMC article.

6

Determinants of durable humoral and T cell immunity in myeloma patients following COVID-19 vaccination.

Twumasi C, Moore S, Sadler R, Jeans S, Varghese S, Turner A, Agarwal G, Larham J, Gray N, Carty O, Barrett J, Bowcock S, Oppermann U, Gamble V, Cook G, Kyriakou C, Drayson M, Basu S, McDonald S, McKinley S, Gooding S, Javaid MK, Ramasamy K. Twumasi C, et al. Among authors: oppermann u. Eur J Haematol. 2024 Apr;112(4):547-553. doi: 10.1111/ejh.14143. Epub 2023 Dec 20. Eur J Haematol. 2024. PMID: 38116695

7

Mass cytometry as a tool in target validation and drug discovery.

Watson ECR, Baker W, Ahern D, Loi D, Cribbs AP, Oppermann U. Watson ECR, et al. Among authors: oppermann u. Methods Enzymol. 2023;690:541-574. doi: 10.1016/bs.mie.2023.07.006. Epub 2023 Oct 5. Methods Enzymol. 2023. PMID: 37858540 Review.

8

BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.

Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, Jegga AG, Oppermann U, Wang Y, Huang W, Jiang L, Pauklin S. Feng Y, et al. Among authors: oppermann u. Gastroenterology. 2024 Jan;166(1):139-154. doi: 10.1053/j.gastro.2023.09.021. Epub 2023 Sep 21. Gastroenterology. 2024. PMID: 37739089 Free article.

9

KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.

Mouti MA, Deng S, Pook M, Malzahn J, Rendek A, Militi S, Nibhani R, Soonawalla Z, Oppermann U, Hwang CI, Pauklin S. Mouti MA, et al. Among authors: oppermann u. Nat Commun. 2023 Sep 14;14(1):5685. doi: 10.1038/s41467-023-41297-4. Nat Commun. 2023. PMID: 37709746 Free PMC article.

10

Phenotypic Chemical Screening in CD4⁺ T Cells to Identify Epigenetic Inhibitors.

Cribbs AP, Oppermann U. Cribbs AP, et al. Among authors: oppermann u. Methods Mol Biol. 2023;2706:225-231. doi: 10.1007/978-1-0716-3397-7_17. Methods Mol Biol. 2023. PMID: 37558953

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