Openshaw RL - Search Results

1

16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability.

Openshaw RL, Thomson DM, Bristow GC, Mitchell EJ, Pratt JA, Morris BJ, Dawson N. Openshaw RL, et al. Commun Biol. 2023 May 24;6(1):557. doi: 10.1038/s42003-023-04891-2. Commun Biol. 2023. PMID: 37225770 Free PMC article.

2

16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia.

Bristow GC, Thomson DM, Openshaw RL, Mitchell EJ, Pratt JA, Dawson N, Morris BJ. Bristow GC, et al. Among authors: openshaw rl. Cell Rep. 2020 Apr 21;31(3):107536. doi: 10.1016/j.celrep.2020.107536. Cell Rep. 2020. PMID: 32320645 Free article.

3

Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions.

Mitchell EJ, Thomson DM, Openshaw RL, Bristow GC, Dawson N, Pratt JA, Morris BJ. Mitchell EJ, et al. Among authors: openshaw rl. Sci Rep. 2020 Jul 23;10(1):12303. doi: 10.1038/s41598-020-69130-8. Sci Rep. 2020. PMID: 32704009 Free PMC article.

4

Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline.

Openshaw RL, Thomson DM, Penninger JM, Pratt JA, Morris BJ. Openshaw RL, et al. Psychopharmacology (Berl). 2017 Jan;234(2):293-305. doi: 10.1007/s00213-016-4463-y. Epub 2016 Oct 24. Psychopharmacology (Berl). 2017. PMID: 27774567 Free PMC article.

5

Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia.

Openshaw RL, Thomson DM, Thompson R, Penninger JM, Pratt JA, Morris BJ, Dawson N. Openshaw RL, et al. Schizophr Bull. 2020 Jan 4;46(1):211-223. doi: 10.1093/schbul/sbz044. Schizophr Bull. 2020. PMID: 31219577 Free PMC article.

6

Impaired working memory, cognitive flexibility and reward processing in mice genetically lacking Gpr88: Evidence for a key role for Gpr88 in multiple cortico-striatal-thalamic circuits.

Thomson DM, Openshaw RL, Mitchell EJ, Kouskou M, Millan MJ, Mannoury la Cour C, Morris BJ, Pratt JA. Thomson DM, et al. Among authors: openshaw rl. Genes Brain Behav. 2021 Feb;20(2):e12710. doi: 10.1111/gbb.12710. Epub 2020 Nov 3. Genes Brain Behav. 2021. PMID: 33078498 Free article.

7

Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction.

Thomson DM, Mitchell EJ, Openshaw RL, Pratt JA, Morris BJ. Thomson DM, et al. Among authors: openshaw rl. J Psychopharmacol. 2021 Oct;35(10):1265-1276. doi: 10.1177/02698811211032439. Epub 2021 Jul 24. J Psychopharmacol. 2021. PMID: 34304635 Free PMC article.

8

The schizophrenia risk gene Map2k7 regulates responding in a novel contingency-shifting rodent touchscreen gambling task.

Openshaw RL, Pratt JA, Morris BJ. Openshaw RL, et al. Dis Model Mech. 2022 Mar 1;15(3):dmm049310. doi: 10.1242/dmm.049310. Epub 2022 Mar 11. Dis Model Mech. 2022. PMID: 35275161 Free PMC article.

9

JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk.

Openshaw RL, Kwon J, McColl A, Penninger JM, Cavanagh J, Pratt JA, Morris BJ. Openshaw RL, et al. J Neuroinflammation. 2019 Jan 28;16(1):18. doi: 10.1186/s12974-019-1408-5. J Neuroinflammation. 2019. PMID: 30691477 Free PMC article.

10

Direct Delivery of MicroRNA96 to the Lungs Reduces Progression of Sugen/Hypoxia-Induced Pulmonary Hypertension in the Rat.

Docherty CK, Denver N, Fisher S, Nilsen M, Hillyard D, Openshaw RL, Labazi H, MacLean MR. Docherty CK, et al. Among authors: openshaw rl. Mol Ther Nucleic Acids. 2020 Sep 6;22:396-405. doi: 10.1016/j.omtn.2020.09.002. eCollection 2020 Dec 4. Mol Ther Nucleic Acids. 2020. PMID: 33230444 Free PMC article.

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