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GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Pairo-Castineira E, Rawlik K, Bretherick AD, Qi T, Wu Y, Nassiri I, McConkey GA, Zechner M, Klaric L, Griffiths F, Oosthuyzen W, Kousathanas A, Richmond A, Millar J, Russell CD, Malinauskas T, Thwaites R, Morrice K, Keating S, Maslove D, Nichol A, Semple MG, Knight J, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Begg C, Walsh T, Tenesa A, Flores C, Riancho JA, Rojas-Martinez A, Lapunzina P; GenOMICC Investigators; SCOURGE Consortium; ISARICC Investigators; 23andMe COVID-19 Team; Yang J, Ponting CP, Wilson JF, Vitart V, Abedalthagafi M, Luchessi AD, Parra EJ, Cruz R, Carracedo A, Fawkes A, Murphy L, Rowan K, Pereira AC, Law A, Fairfax B, Hendry SC, Baillie JK. Pairo-Castineira E, et al. Among authors: openshaw pjm. Nature. 2023 May;617(7962):764-768. doi: 10.1038/s41586-023-06034-3. Epub 2023 May 17. Nature. 2023. PMID: 37198478 Free PMC article.
Development of vaccines against common colds.
Olszewska W, Zambon M, Openshaw PJ. Olszewska W, et al. Br Med Bull. 2002;62:99-111. doi: 10.1093/bmb/62.1.99. Br Med Bull. 2002. PMID: 12176853 Review.
Impact of the 2009 influenza pandemic.
Dunning J, Openshaw PJ. Dunning J, et al. Thorax. 2010 Jun;65(6):471-2. doi: 10.1136/thx.2009.133728. Thorax. 2010. PMID: 20522840 No abstract available.
Predictors of clinical outcome in a national hospitalised cohort across both waves of the influenza A/H1N1 pandemic 2009-2010 in the UK.
Myles PR, Semple MG, Lim WS, Openshaw PJ, Gadd EM, Read RC, Taylor BL, Brett SJ, McMenamin J, Enstone JE, Armstrong C, Bannister B, Nicholson KG, Nguyen-Van-Tam JS; Influenza Clinical Information Network (FLU-CIN). Myles PR, et al. Thorax. 2012 Aug;67(8):709-17. doi: 10.1136/thoraxjnl-2011-200266. Epub 2012 Mar 10. Thorax. 2012. PMID: 22407890 Free PMC article.
IFITM3 restricts the morbidity and mortality associated with influenza.
Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE, Chin CR, Feeley EM, Sims JS, Adams DJ, Wise HM, Kane L, Goulding D, Digard P, Anttila V, Baillie JK, Walsh TS, Hume DA, Palotie A, Xue Y, Colonna V, Tyler-Smith C, Dunning J, Gordon SB; GenISIS Investigators; MOSAIC Investigators; Smyth RL, Openshaw PJ, Dougan G, Brass AL, Kellam P. Everitt AR, et al. Nature. 2012 Mar 25;484(7395):519-23. doi: 10.1038/nature10921. Nature. 2012. PMID: 22446628 Free PMC article.
M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.
Cole SL, Dunning J, Kok WL, Benam KH, Benlahrech A, Repapi E, Martinez FO, Drumright L, Powell TJ, Bennett M, Elderfield R, Thomas C; MOSAIC investigators; Dong T, McCauley J, Liew FY, Taylor S, Zambon M, Barclay W, Cerundolo V, Openshaw PJ, McMichael AJ, Ho LP. Cole SL, et al. JCI Insight. 2017 Apr 6;2(7):e91868. doi: 10.1172/jci.insight.91868. JCI Insight. 2017. PMID: 28405622 Free PMC article.
262 results